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Genetic variants in BRIP1 (BACH1) contribute to risk of nonsyndromic cleft lip …

Mostowska(Adrianna),Hozyasz(Kamil K),Wójcick… Birth Defects Res A Clin Mol … 2015-05-21

...RAD50, and RAD51) was conducted using TaqMan assays in a group of 263 NSCL/P patients and matched control group (n = 526...

Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells.

Acharya(Samir),Kaul(Zeenia),Gocha(April Sand… PLoS One 2015-04-23

...RAD50 at telomeres during S- and G2-phases of the cell cycle in immortalized human cells using ALT but not in cells usin...

Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN con…

Damiola(Francesca),Pertesi(Maroulio),Oliver(… Breast Cancer Res 2015-04-16

The MRE11A-RAD50-Nibrin (MRN) complex plays several critical roles related to repair of DNA double-strand breaks. Inheri...

A polymorphism in the TH 2 locus control region is associated with changes in D…

Schieck(M),Sharma(V),Michel(S),Toncheva(A A)… Allergy 2015-04-02

Genomewide association and epigenetic studies found a region within the RAD50 gene on chromosome 5q31 to be associated w...

Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vit…

Koppensteiner(Romana),Samartzis(Eleftherios … PLoS One 2015-12-09

To evaluate the frequency of MRE11/RAD50/NBS1 (MRN)-complex loss of protein expression in endometrial cancers (EC) and t...

Fine-mapping of IgE-associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Pr…

Sharma(V),Michel(S),Gaertner(V),Franke(A),Vo… Allergy 2015-06-24

...RAD50-IL13 and IL4), and 12q13 (STAT6) as major susceptibility loci influencing the regulation of total serum IgE levels...

Structure of the hexameric HerA ATPase reveals a mechanism of translocation-cou…

Rzechorzek(Neil J),Blackwood(John K),Bray(Si… Nat Commun 2015-10-15

...Rad50 complex for the repair of double-strand DNA breaks in thermophilic archaea. Here we extend our structural knowledg...

Molecular architecture of the HerA-NurA DNA double-strand break resection compl…

Byrne(Robert Thomas),Schuller(Jan Michael),U… FEBS Lett 2015-02-17

...Rad50 complex and the ATP-dependent helicase-nuclease complex HerA-NurA. We report the cryo-EM structure of Sulfolobus s...

NBN gain is predictive for adverse outcome following image-guided radiotherapy …

Berlin(Alejandro),Lalonde(Emilie),Sykes(Jenn… Oncotarget 2015-08-25

...RAD50, NBN, ATM, ATR and PRKDC. We studied copy number alterations in DDR genes in localized PCa treated with image-guid...

Regulation of DNA damage responses and cell cycle progression by hMOB2.

Gomez(Valenti),Gundogdu(Ramazan),Gomez(Marta… Cell Signal 2015-08-25

...RAD50, facilitating the recruitment of the MRE11-RAD50-NBS1 (MRN) DNA damage sensor complex and activated ATM to DNA dam...

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