The centromere is essential for the segregation of chromosomes, as it serves as attachment site for microtubules to medi...
Centromere-specific nucleosomes are a central feature of the kinetochore complex during mitosis, in which microtubules e...
Xeroderma pigmentosum group A (XPA)-binding protein 2 (XAB2) is a multi-functional protein that plays critical role in p...
Chromosome alignment is required for accurate chromosome segregation. Chromosome misalignment can result in genomic inst...
Replication, segregation, gene expression, and inheritance are essential features of all eukaryotic chromosomes. To deli...
The Mis18 proteins (Mis18α, Mis18β, and M18BP1) are pivotal to the deposition of CENP-A at the centromere during cell cy...
Human centromeres contain large amounts of repetitive DNA sequences known as α satellite DNA, which can be difficult to ...
Human centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive alphoid DN...
Kinetochores, multisubunit protein assemblies, connect chromosomes to spindle microtubules to promote chromosome segrega...
Chromosome missegregation into a micronucleus can cause complex and localized genomic rearrangements known as chromothri...
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