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Amyloid precursor protein regulates brain apolipoprotein E and cholesterol meta…

Liu(Q),Zerbinatti(CV),Zhang(J),Hoe(HS),Wang(… Neuron 2007-10-04

...APLP2, or components of the gamma-secretase complex, significantly enhanced the expression and function of LRP1, which w...

Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer's…

Bayer(TA),Paliga(K),Weggen(S),Wiestler(OD),B… Acta Neuropathol 1997-12-00

...APLP2) are members of a super-family of proteins that appear functionally related. Although APLPs are highly homologous ...

Homo- and heterodimerization of APP family members promotes intercellular adhes…

Soba(P),Eggert(S),Wagner(K),Zentgraf(H),Sieh… EMBO J 2005-10-19

...APLP2 is required for cell-cell adhesion in mouse embryonic fibroblasts. We further demonstrate interaction of all the t...

Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation…

Cao(Q),Huang(YS),Kan(MC),Richter(JD) Mol Cell Biol 2005-12-00

...APLP2 and APP. These proteins promote polyadenylation and translation by stimulating Aurora A catalyzed CPEB serine 174 ...

Detection of the retinoic acid-regulated genes in a RTBM1 neuroblastoma cell li…

Ueda(K) Kurume Med J 2001-00-00

...APLP2), P311, dihydropyrimidinase related protein3 (DRP3) and RGP4 were up-regulated, while 2 genes, Id-2 and vimentin, ...

The amyloid precursor protein affects glyceraldehyde 3-phosphate dehydrogenase …

Delport(A),Kins(S),Hewer(R) Mol Biol Rep 2020-04-00

...APLP2 were used. Heterologous expression of APP695 was shown to increase the level of GAPDH within the cytoplasm by over...

Interference of human and Drosophila APP and APP-like proteins with PNS develop…

Merdes(G),Soba(P),Loewer(A),Bilic(MV),Beyreu… EMBO J 2004-10-13

...APLP2 induce Notch gain-of-function phenotypes, identified Numb as a potential target and provided evidence for a direct...

Amyloid precursor protein is a biomarker for transformed human pluripotent stem…

Venkataramani(V),Thiele(K),Behnes(CL),Wulf(G… Am J Pathol 2012-04-00

...APLP2, showed no correlation to these stem cell factors. In addition, treatment with histone deacetylase (HDAC) inhibito...

Essential roles for the FE65 amyloid precursor protein-interacting proteins in …

Guénette(S),Chang(Y),Hiesberger(T),Richardso… EMBO J 2006-01-25

...APLP2, all of which interact with FE65 proteins, suggesting that this phenotype may be caused by decreased transmission ...

Presenilin-dependent transcriptional control of the Abeta-degrading enzyme nepr…

Pardossi-Piquard(R),Petit(A),Kawarai(T),Suny… Neuron 2005-05-19

...APLP2), but not by Abeta or by the gamma-secretase cleavage products of Notch, N- or E- cadherins. The presenilin-depend...

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