...APLP2, or components of the gamma-secretase complex, significantly enhanced the expression and function of LRP1, which w...
...APLP2) are members of a super-family of proteins that appear functionally related. Although APLPs are highly homologous ...
...APLP2 is required for cell-cell adhesion in mouse embryonic fibroblasts. We further demonstrate interaction of all the t...
...APLP2 and APP. These proteins promote polyadenylation and translation by stimulating Aurora A catalyzed CPEB serine 174 ...
...APLP2), P311, dihydropyrimidinase related protein3 (DRP3) and RGP4 were up-regulated, while 2 genes, Id-2 and vimentin, ...
...APLP2 were used. Heterologous expression of APP695 was shown to increase the level of GAPDH within the cytoplasm by over...
...APLP2 induce Notch gain-of-function phenotypes, identified Numb as a potential target and provided evidence for a direct...
...APLP2, showed no correlation to these stem cell factors. In addition, treatment with histone deacetylase (HDAC) inhibito...
...APLP2, all of which interact with FE65 proteins, suggesting that this phenotype may be caused by decreased transmission ...
...APLP2), but not by Abeta or by the gamma-secretase cleavage products of Notch, N- or E- cadherins. The presenilin-depend...
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