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Point mutation impairs centromeric CENH3 loading and induces haploid plants.

Karimi-Ashtiyani(Raheleh),Ishii(Takayoshi)... Proc Natl Acad Sci U S A 2016-01-06

The chromosomal position of the centromere-specific histone H3 variant CENH3 (also called "CENP-A") is the assembly site...

Clinical correlates of a subset of anti-CENP-A antibodies cross-reacting with...

Perosa(Federico),Favoino(Elvira),Cuomo(Gio... Arthritis Res Ther 2015-09-10

In a subset of patients with limited cutaneous (lc) systemic sclerosis (SSc), anti-CENP-A antibodies (Ab) cross-react wi...

Humoral autoimmune response heterogeneity in the spectrum of primary biliary ...

Dellavance(Alessandra),Cançado(Eduardo Lui... Hepatol Int 2015-07-28

To compare autoantibody features in patients with primary biliary cirrhosis (PBC) and individuals presenting antimitocho...

Cerium oxide nanoparticles accelerate the decay of peroxynitrite (ONOO(-)).

Dowding(Janet M),Seal(Sudipta),Self(Willia... Drug Deliv Transl Res 2015-05-08

...CeNPs with the carbonate radical anion. These results suggest that one of the protective effects of CeO2 NPs during RNS ...

CENP-A is essential for cardiac progenitor cell proliferation.

McGregor(Michael),Hariharan(Nirmala),Joyo(... Cell Cycle 2015-05-11

Centromere protein A (CENP-A) is a homolog of histone H3 that epigenetically marks the heterochromatin of chromosomes. C...

Visualization of specific DNA sequences in living mouse embryonic stem cells ...

Anton(Tobias),Bultmann(Sebastian),Leonhard... Nucleus 2015-01-22

Labeling and tracing of specific sequences in living cells has been a major challenge in studying the spatiotemporal dyn...

The CENP-O complex requirement varies among different cell types.

Kagawa(Naoko),Hori(Tetsuya),Hoki(Yuko),Hos... Chromosome Res 2015-09-21

CENP-U (CENP-50) is a component of the CENP-O complex, which includes CENP-O, CENP-P, CENP-Q, CENP-R, and CENP-U and is ...

Naturally occurring differences in CENH3 affect chromosome segregation in zyg...

Maheshwari(Shamoni),Tan(Ek Han),West(Allan... PLoS Genet 2015-08-07

The point of attachment of spindle microtubules to metaphase chromosomes is known as the centromere. Plant and animal ce...

CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric...

Athwal(Rajbir K),Walkiewicz(Marcin P),Baek... Epigenetics Chromatin 2015-03-19

The histone H3 variant CENP-A is normally tightly regulated to ensure only one centromere exists per chromosome. Native ...

Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at hu...

Kim(Soonjoung),Yu(Hongtao) J Cell Biol 2015-03-20

During mitosis, the spindle checkpoint senses kinetochores not properly attached to spindle microtubules and prevents pr...

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