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TP53 BRCA1 CRISPR single-cell cancer

Lopes da Rosa(Jessica),Holik(John),Green(Eri… Genetics 2011-04-20

Accurate chromosome segregation is dependent on the centromere-specific histone H3 isoform known generally as CenH3, or ...

Corbett(Kevin D),Yip(Calvin K),Ee(Ly-Sha),Wa… Cell 2010-09-14

The monopolin complex regulates different types of kinetochore-microtubule attachments in fungi, ensuring sister chromat...

Osakabe(Akihisa),Tachiwana(Hiroaki),Matsunag… J Biol Chem 2010-05-06

NASP (nuclear autoantigenic sperm protein) is a member of the N1/N2 family, which is widely conserved among eukaryotes. ...

Fernández-Miranda(Gonzalo),Pérez de Castro(I… J Cell Sci 2010-12-02

Aurora kinases are central regulators of mitotic-spindle assembly, chromosome segregation and cytokinesis. Aurora B is a...

Tran Nguyen(TM),Munhoven(A),Samel-Pommerenck… Genetics 2023-00-06

Post-translational modifications on histones are well known to regulate chromatin structure and function, but much less ...

Macaisne(N),Bellutti(L),Laband(K),Edwards(F)… Elife 2023-00-17

During cell division, chromosome segregation is orchestrated by a microtubule-based spindle. Interaction between spindle...

Macchia(Gemma),Nord(Karolin H),Zoli(Monica),… Genes Chromosomes Cancer 2015-09-23

Gene amplification is relatively common in tumors. In certain subtypes of sarcoma, it often occurs in the form of ring a...

Dou(Z),Qiu(C),Zhang(X),Yao(S),Zhao(C),Wang(Z… Int J Biol Sci 2022-00-00

Ovarian cancer is the most lethal gynecological malignancy. Recurrence and chemoresistance are tough challenges leading ...

Su(W),Huang(B),Zhang(Q),Han(W),An(L),Guan(Y)… J Healthc Eng 2022-00-00

Cutaneous squamous cell carcinoma (cSCC) is the leading cause of death in patients with nonmelanoma skin cancers (NMSC)....

Zeng(Z),Wang(Z),Chen(S),Xiao(C),Liu(M),Zhang… J Nanobiotechnology 2022-11-24

...CeNPs) with peroxidase activity were synthesized to autonomously generate O2 by decomposing H2O2 within tumor region and...

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