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TP53 BRCA1 CRISPR single-cell cancer

Zhao(X),Li(W) Mol Genet Genomic Med 2019-00-00

Gestational diabetes mellitus (GDM) is one of the most common problems during pregnancy. Lack of international consisten...

Malik(N),Dantu(SC),Shukla(S),Kombrabail(M),G… J Biol Chem 2018-00-28

The histone variant CENP-ACse4 is a core component of the specialized nucleosome at the centromere in budding yeast and ...

Bell(C),Chen(L),Maristany(MJ),Blaukopf(C),Zh… bioRxiv 2025-09-02

During cell division, chromosomes reorganise into compact bodies in which centromeres localise precisely at the chromati...

Laffitte(A),Lin(D),Tian(YJ),Liu(N),Lusk(CP),… Genes Dev 2025-12-23

While homologous recombination (HR) is often considered to be an error-free DNA repair mechanism, the fidelity of this p...

Eli(S),Rauso(G),Ghezzi(P),Szczerkowski(JLA),… Nat Commun 2025-11-27

In multicellular organisms, the execution of developmental and homeostatic programs often relies on asymmetric cell divi...

Laffitte(A),Lin(D),Tian(YJ),Liu(N),Lusk(CP),… bioRxiv 2025-10-09

While homologous recombination (HR) is often considered to be an error-free DNA repair mechanism, the fidelity of this p...

Brimacombe(CA),Burke(JE),Parsa(JY),Catania(S… PLoS Biol 2019-00-00

Eukaryotes have evolved elaborate mechanisms to ensure that chromosomes segregate with high fidelity during mitosis and ...

Zhang(J),Zhong(L),Yi(X),Yao(X),Wen(Y),Yang(J… Sci Rep 2025-10-22

Sleep disturbance is increasingly common and has been linked to adverse metabolic outcomes. This study investigated whet...

Leem(J),Lemonnier(T),Khutsaidze(A),Tian(L),X… bioRxiv 2025-02-27

Female reproductive aging is accompanied by a dramatic rise in the incidence of egg aneuploidy. Premature loss of chromo...

Gangwar(M),Kumar(S),Ahmad(SF),Singh(A),Agarw… Trop Anim Health Prod 2025-03-06

The present study delves into the relationship between single nucleotide polymorphisms (SNPs) and production performance...

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