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TP53 BRCA1 CRISPR single-cell cancer

Liu(K),Wang(Y),Ye(Z),Chen(Z),Liang(Y),Shen(F… Cardiovasc Toxicol 2025-05-00

Ascending aortic dilation (AAD) is a complex and life-threatening condition, representing a significant risk factor for ...

Serpico(AF),Visconti(R),Grieco(D) Cell Death Dis 2020-00-12

Microtubule-targeting agents (MTAs), like taxanes and vinca alkaloids, are tubulin-binding drugs that are very effective...

Mohammadian Gol(T),Rodemann(HP),Dittmann(K) Int J Mol Sci 2019-12-14

Homologous recombination repair (HRR), non-homologous end-joining (NHEJ) and alternative NHEJ are major pathways that ar...

Shahnejat-Bushehri(S),Ehrenhofer-Murray(AE) Proc Natl Acad Sci U S A 2020-00-10

The AAA+ ATPase and bromodomain factor ATAD2/ANCCA is overexpressed in many types of cancer, but how it contributes to t...

Caro Pérez(Alejandro),Kumble(Sarita),Kumble(… Autoimmune Dis 2014-02-14

The performance of immunoassays for the detection of autoantibodies is of critical importance in the diagnosis and asses...

DeRycke(Melissa S),Gunawardena(Shanaka R),Mi… Cancer Epidemiol Biomarkers P… 2013-11-06

Colorectal cancer (CRC) in densely affected families without Lynch Syndrome may be due to mutations in undiscovered gene...

Akiyoshi(Bungo),Nelson(Christian R),Duggan(N… PLoS Genet 2013-06-13

The kinetochore is the macromolecular complex that assembles onto centromeric DNA and orchestrates the segregation of du...

Fu(Shulan),Lv(Zhenling),Gao(Zhi),Wu(Huajun),… Proc Natl Acad Sci U S A 2013-07-12

The centromere is the part of the chromosome that organizes the kinetochore, which mediates chromosome movement during m...

Parker(Jennifer C),Bunn(Christopher C) J Clin Pathol 2011-11-04

To evaluate the sensitivity of a commercial autoantibody screening method (Phadia EliA connective tissue disease (CTD) s...

Osakabe(Akihisa),Tachiwana(Hiroaki),Matsunag… J Biol Chem 2010-05-06

NASP (nuclear autoantigenic sperm protein) is a member of the N1/N2 family, which is widely conserved among eukaryotes. ...

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