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Overlapping regulation of CenH3 localization and histone H3 turnover by CAF-1 a…

Lopes da Rosa(Jessica),Holik(John),Green(Eri… Genetics 2011-04-20

Accurate chromosome segregation is dependent on the centromere-specific histone H3 isoform known generally as CenH3, or ...

The monopolin complex crosslinks kinetochore components to regulate chromosome-…

Corbett(Kevin D),Yip(Calvin K),Ee(Ly-Sha),Wa… Cell 2010-09-14

The monopolin complex regulates different types of kinetochore-microtubule attachments in fungi, ensuring sister chromat...

SUMOylation modulates the function of Aurora-B kinase.

Fernández-Miranda(Gonzalo),Pérez de Castro(I… J Cell Sci 2010-12-02

Aurora kinases are central regulators of mitotic-spindle assembly, chromosome segregation and cytokinesis. Aurora B is a...

SUMO chains: polymeric signals.

Vertegaal(Alfred C O) Biochem Soc Trans 2010-03-15

Ubiquitin and ubiquitin-like proteins are conjugated to a wide variety of target proteins that play roles in all biologi...

Visualization of specific DNA sequences in living mouse embryonic stem cells wi…

Anton(Tobias),Bultmann(Sebastian),Leonhardt(… Nucleus 2015-01-22

Labeling and tracing of specific sequences in living cells has been a major challenge in studying the spatiotemporal dyn...

Potential key molecular correlations in laryngeal squamous cell carcinoma revea…

Zhang(C),Gao(W),Wen(S),Wu(Y),Fu(R),Zhao(D),C… Neoplasma 0000-00-00

To uncover potential key genes, microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) associated with laryngeal squamous...

Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in…

Kuenzel(NA),Alcázar-Román(AR),Saiardi(A),Bar… J Fungi (Basel) 2022-09-02

Inositol pyrophosphates (IPPs) comprise a specific class of signaling molecules that regulate central biological process...

De novo POGZ mutations in sporadic autism disrupt the DNA-binding activity of P…

Matsumura(Kensuke),Nakazawa(Takanobu),Nagaya… J Mol Psychiatry 2016-04-22

A spontaneous de novo mutation is a new mutation appeared in a child that neither the parent carries. Recent studies sug...

Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetoc…

Normandin(K),Coulombe-Huntington(J),St-Denis… PLoS Genet 2023-00-00

Polo-like kinase 1 (PLK1) is a serine/threonine kinase required for mitosis and cytokinesis. As cancer cells are often h...

NCAPG Promotes Pulmonary Artery Smooth Muscle Cell Proliferation as a Promising…

Fu(B),Li(Y),Shi(X),Liu(P),Zhang(Y),Tian(H) Int J Mol Sci 2022-10-04

Idiopathic pulmonary arterial hypertension (IPAH) is a disease with complex etiology. Currently, IPAH treatment is limit...

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