Acx(H),Serneels(L),Radaelli(E),Muyldermans(S… EMBO Mol Med 2017-00-00

...Aplp2, Lrp1, and Sdc3 accumulate to lesser extents. Despite numerous reports linking neurodegeneration to accumulation o...

Paschkowsky(S),Hamzé(M),Oestereich(F),Munter… J Biol Chem 2016-10-14

...APLP2 to be substrates of RHBDL4. We conclude that RHBDL4-mediated APP processing provides insight into APP and rhomboid...

Song(P),Pimplikar(SW) PLoS One 2012-00-00

...APLP2) genes in mice results in post-natal lethality, suggesting that APP performs an essential, if redundant, function ...

Pavic(K),Hood(FE),Duval(CJ),Manoharan(GB),La… iScience 2025-12-19

...APLP2, which indirectly engages with C-Raf in immediate proximity to K-Ras, and SPRY2, which exhibits properties of an e...

DeVay(RM),Shelton(DL),Liang(H) J Biol Chem 2013-04-12

Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates low density lipoprotein receptor protein levels by diver...

Zhao(CC),Yu(WW),Qi(YJ),Xu(LF),Wang(ZR),Qiang… Anticancer Drugs 2020-00-00

...APLP2, CYR61, CD63, ENG, and CD9. Our observation on protein expression indicated that LukS-PV produces a signature affe...

Kaden(D),Munter(LM),Reif(B),Multhaup(G) Eur J Cell Biol 2012-04-00

...APLP2) decreased Aβ formation. This review mainly focuses on structural features of the homophilic and heterophilic inte...

Scheinfeld(MH),Ghersi(E),Davies(P),D'Adamio(… J Biol Chem 2003-10-24

...APLP2. Understanding the connection between AbetaPP phosphorylation and the JNK signaling pathway, which mediates cell r...

Fahrenholz(F) Curr Alzheimer Res 2007-09-00

...APLP2), and led to an enhanced secretion of their extracellular domains. Furthermore, G protein-coupled receptors (GPCRs...

Checler(F),Sunyach(C),Pardossi-Piquard(R),Sé… Curr Alzheimer Res 2007-09-00

...APLP2 depletion reduced the expression and activity of p53, and lowered the transactivation of its promoter and mRNA lev...