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De La Fuente(Rabindranath),Baumann(Claudia... Development 2015-08-19

A striking proportion of human cleavage-stage embryos exhibit chromosome instability (CIN). Notably, until now, no exper...

Fang(Junnan),Liu(Yuting),Wei(Yun),Deng(Wen... Genes Dev 2015-07-21

Specific recognition of centromere-specific histone variant CENP-A-containing chromatin by CENP-N is an essential proces...

Falk(Samantha J),Guo(Lucie Y),Sekulic(Niko... Science 2015-06-22

Inheritance of each chromosome depends upon its centromere. A histone H3 variant, centromere protein A (CENP-A), is esse...

Fujita(Risa),Otake(Koichiro),Arimura(Yasuh... Nucleic Acids Res 2015-08-17

CENP-A and CENP-B are major components of centromeric chromatin. CENP-A is the histone H3 variant, which forms the centr...

Milev(Miroslav P),Hasaj(Benedeta),Saint-Di... J Cell Biol 2015-07-09

Chromosome congression requires the stable attachment of microtubules to chromosomes mediated by the kinetochore, a larg...

Morozzi(Gabriella),Bellisai(Francesca),Fin... Auto Immun Highlights 2015-05-22

The aim of our study was to determine the prevalence, clinical significance of antibodies to individual histone componen...

Batzenschlager(Morgane),Lermontova(Inna),S... Proc Natl Acad Sci U S A 2015-10-30

Centromeres play a pivotal role in maintaining genome integrity by facilitating the recruitment of kinetochore and siste...

Klare(Kerstin),Weir(John R),Basilico(Feder... J Cell Biol 2015-10-05

Kinetochores are multisubunit complexes that assemble on centromeres to bind spindle microtubules and promote faithful c...

Volkov(Vladimir A),Grissom(Paula M),Arzhan... J Cell Biol 2015-09-10

Firm attachments between kinetochores and dynamic spindle microtubules (MTs) are important for accurate chromosome segre...

Chen(Chin-Chi),Bowers(Sarion),Lipinszki(Zo... Dev Cell 2015-09-28

Centromeres are essential chromosomal structures that mediate accurate chromosome segregation during cell division. Cent...