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ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stres…

Bao(S),Tibbetts(R S),Brumbaugh(K M),Fang(Y),… Nature 2001-07-05

...Rad17 at Ser 635 and Ser 645. Overexpression of a hRad17 mutant (hRad17AA) bearing Ala substitutions at both phosphoryla...

Characterization of DNA damage-stimulated self-interaction of Saccharomyces cer…

Zhang(H),Zhu(Z),Vidanes(G),Mbangkollo(D),Liu… J Biol Chem 2001-08-16

...Rad17p interactions with Rad17p or Mec3p, single amino acid substitutions revealed that Rad17p x Rad17p complex formatio...

Suppression of spontaneous chromosomal rearrangements by S phase checkpoint fun…

Myung(K),Datta(A),Kolodner(R D) Cell 2001-04-12

...RAD17, RAD24, BUB3, and MAD3 had little effect. The rearrangements were primarily deletion of a portion of a chromosome ...

Analysis of candidate genes included in the mammary cancer susceptibility 1 (Mc…

Laes(J F),Quan(X),Ravoet(M),Stieber(D),Van V… Mamm Genome 2001-08-23

...Rad17, and Naip, were excluded from the critical region. Since cyclin H, encoded by Ccnh, plays an important role in the...

Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated a…

Post(S),Weng(Y C),Cimprich(K),Chen(L B),Xu(Y… Proc Natl Acad Sci U S A 2001-12-07

...Rad17 (hRad17) checkpoint protein on Ser(635) and Ser(645) in vitro. In undamaged synchronized human cells, these two si...

Overexpression of Hrad17 gene in non-small cell lung cancers correlated with ly…

Sasaki(H),Chen(L B),Auclair(D),Moriyama(S),K… Lung Cancer 2001-12-04

...rad17 may be expressed in non-small cell lung cancer (NSCLC). We attempted to determine the influence of Hrad17 expressi...

Overexpression of HRad17 mRNA in human breast cancer: correlation with lymph no…

Kataoka(A),Sadanaga(N),Mimori(K),Ueo(H),Barn… Clin Cancer Res 2001-10-04

...Rad17, was identified as the human homologue of the Rad17 of Schizosaccharomyces pombe and Rad24 of Saccharomyces cerevi...

Two checkpoint complexes are independently recruited to sites of DNA damage in …

Melo(J A),Cohen(J),Toczyski(D P) Genes Dev 2001-12-07

The Ddc1/Rad17/Mec3 complex and Rad24 are DNA damage checkpoint components with limited homology to replication factors ...

Multiple alternative splicing forms of human RAD17 and their differential respo…

Chen(M S),Higashikubo(R),Laszlo(A),Roti Roti… Gene 2001-12-13

In this study, we have identified four alternatively spliced RAD17 RNAs, FM1, FM2, FM3, and FM4, which are produced thro...

Sgs1 helicase activity is required for mitotic but apparently not for meiotic f…

Miyajima(A),Seki(M),Onoda(F),Shiratori(M),Od… Mol Cell Biol 2000-09-21

...RAD17 gene partially alleviated the poor-sporulation phenotype of sgs1 disruptants, indicating that portions of the popu...

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