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The role of OsCOM1 in homologous chromosome synapsis and recombination in rice …

Ji(Jianhui),Tang(Ding),Wang(Kejian),Wang(Mo)… Plant J 2014-01-10

...Rad50/Xrs2), are required for meiotic DNA double-strand break (DSB) ends resection and specific mitotic DSB repair event...

Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in h…

Kuusisto(Kirsi M),Bebel(Aleksandra),Vihinen(… Breast Cancer Res 2014-03-25

...RAD50, and CDH1. BRCA1/2 were analyzed by multiplex ligation-dependent probe amplification (MLPA) and direct sequencing....

The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and…

Mason(Jennifer M),Das(Ishita),Arlt(Martin),P… Hum Mol Genet 2014-07-22

...RAD50/NBS1 complex to aphidicolin-induced foci. We determined that a major consequence of SNM1B depletion is a marked in...

Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid…

Passaro(Carmela),Abagnale(Antonella),Liberti… Endocr Relat Cancer 2014-03-03

...Rad50-Nbs1), accumulation of γH2AX, and activation of the checkpoint kinases ataxia telangiectasia mutated (ATM) and Chk...

MRE11 is required for homologous synapsis and DSB processing in rice meiosis.

Ji(Jianhui),Tang(Ding),Wang(Mo),Li(Yafei),Zh… Chromosoma 2014-03-26

...Rad50 and Nbs1/Xrs2 to form a complex (MRN/X) that participates in double-strand break (DSB) ends processing. In this st...

Human candidate polymorphisms in sympatric ethnic groups differing in malaria s…

Maiga(Bakary),Dolo(Amagana),Touré(Ousmane),D… PLoS One 2014-06-23

...RAD50, TNF, SLC22A4, and IL13 genes were correlated with antibody production (p-value<0.003). Further work is required t...

Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial …

Zhang(Zhan),Lu(Huiyuan),Huan(Fei),Meghan(Cro… Int J Cancer 2014-04-17

...Rad50 and Rad51. However, the apoptosis of P40 cells was near normal, while the expression of Bax, C-Caspase 3 and C-PAR...

A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independe…

Crown(K Nicole),Savytskyy(Oleksandr P),Malik… G3 (Bethesda) 2014-06-09

Nbs1, a core component of the Mre11-Rad50-Nbs1 complex, plays an essential role in the cellular response to DNA double-s...

A DNA break inducer activates the anticodon nuclease RloC and the adaptive immu…

Klaiman(Daniel),Steinfels-Kohn(Emmanuelle),K… Nucleic Acids Res 2014-02-21

...Rad50 and the antiviral, translation-disabling ACNase PrrC. While PrrC's ACNase is regulated by a DNA restriction-modifi...

Defining the contribution of SNPs identified in asthma GWAS to clinical variabl…

Tulah(Asif S),Holloway(John W),Sayers(Ian) BMC Med Genet 2014-01-06

...RAD50 did not show association with any phenotype tested when corrected for multiple testing. Analysis using ENCODE data...

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