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TP53 BRCA1 CRISPR single-cell cancer

Averbeck(NB),Barent(C),Jakob(B),Syzonenko(T)… Cells 2022-00-17

DNA double-strand breaks (DSBs) represent the molecular origin of ionizing-radiation inflicted biological effects. An in...

Kim(J),Lee(S),Lee(J),Park(JC),Kim(KH),Ko(JM)… Mol Genet Metab 2022-00-00

Phenylketonuria (PKU) is a common genetic metabolic disorder that causes phenylalanine accumulation in the blood. The mo...

Trivedi(M),Gianfrate(F),de Gennaro(L),Ayllon… bioRxiv 2026-05-19

Centromeres represent essential chromosomal structures required for faithful chromosome segregation during cell division...

Xu(C),Su(W),Jiang(X) J Craniofac Surg 2020-00-00

Gene alterations are very vital when it comes to the molecular pathogenesis of glioma. In this study, there was the desi...

Senaratne(AP),Muller(H),Fryer(KA),Kawamoto(M… Curr Biol 2021-00-11

Despite the essentiality for faithful chromosome segregation, centromere architectures are diverse among eukaryotes1,2 a...

Arshad(F),Varghese(F),Paplikar(A),Gangadhar(… Dement Geriatr Cogn Disord 2021-00-00

In the background of an emerging role for immune dysregulation in neurodegenerative dementias, this study aimed to inves...

Hartley(GA),Okhovat(M),O'Neill(RJ),Carbone(L) Mol Biol Evol 2021-08-23

Centromeres are functionally conserved chromosomal loci essential for proper chromosome segregation during cell division...

Gu(Y),Wu(H),Wang(T),Yu(S),Han(Z),Zhang(W),Mu… Cell Mol Neurobiol 2021-08-02

Hippocampal sclerosis (HS) is the most common surgical pathology associated with temporal lobe epilepsy (TLE). However, ...

Rosin(LF),Gil(J),Drinnenberg(IA),Lei(EP) PLoS Genet 2021-00-00

Accurate chromosome segregation during meiosis is essential for reproductive success. Yet, many fundamental aspects of m...

Iegiani(G),Di Cunto(F),Pallavicini(G) Cell Death Dis 2021-00-18

Medulloblastoma (MB) and gliomas are the most frequent high-grade brain tumors (HGBT) in children and adulthood, respect...

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