Walsh(DM),Fadeeva(JV),LaVoie(MJ),Paliga(K),E… Biochemistry 2003-06-10

...APLP2. Although APP and the APLPs undergo similar proteolytic processing, there is little information about the role of ...

Alves da Costa(C),Sunyach(C),Pardossi-Piquar… J Neurosci 2006-06-07

...APLP2) depletion all reduce the expression and activity of p53 and lower the transactivation of its promoter and mRNA ex...

Schilling(S),August(A),Meleux(M),Conradt(C),… Cell Biosci 2023-08-02

...APLP2. They share similar structures, form homo- and heterotypic dimers and exhibit overlapping functions. We investigat...

Steubler(V),Erdinger(S),Back(MK),Ludewig(S),… EMBO J 2021-00-15

...APLP2 triple KO (cTKO) mice lacking the APP family in excitatory forebrain neurons from embryonic day 11.5 onwards. NexC...

Schwarz(JJ),Grundmann(L),Kokot(T),Kläsener(K… Life Sci Alliance 2021-00-00

...APLP2 as specific substrates of PTP1B in Ramos B cells. The tyrosine kinase BTK and the two adaptor proteins GRB2 and VA...

Young-Pearse(TL),Chen(AC),Chang(R),Marquez(C… Neural Dev 2008-06-23

...APLP2, homologues of APP, likewise stimulates neurite lengthening. Intriguingly, wild-type neurons exposed to APPs-alpha...

Maynard(DM),Heijnen(HF),Horne(MK),White(JG),… J Thromb Haemost 2007-09-00

...APLP2, ESAM and LAMA5 in platelet alpha-granules for the first time. We identified 65% of the same proteins that were de...

Scheinfeld(MH),Ghersi(E),Laky(K),Fowlkes(BJ)… J Biol Chem 2002-11-15

...APLP2), are also processed by the gamma-secretase in a Presenilin 1-dependent manner. Furthermore, the extreme carboxyl-...

Mirinics(ZK),Calafat(J),Udby(L),Lovelock(J),… Blood Cells Mol Dis 2002-00-00

...APLP2. Notch directs neural and hematopoietic development. Here we show mRNA and protein expression of PS1 in both lymph...

Stante(M),Minopoli(G),Passaro(F),Raia(M),Vec… Proc Natl Acad Sci U S A 2009-03-31

...APLP2 suppression results in the impairment of recruitment of Tip60-TRRAP complex to DNA double strand breaks, decreased...