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TP53 BRCA1 CRISPR single-cell cancer

Doherty(Kevin),Meere(Martin),Piiroinen(Pet... Math Biosci 2015-05-15

Centromere Protein A (CENP-A) is a histone H3 variant found at mammalian centromeres. Unlike canonical histones which ar...

McGregor(Michael),Hariharan(Nirmala),Joyo(... Cell Cycle 2015-05-11

Centromere protein A (CENP-A) is a homolog of histone H3 that epigenetically marks the heterochromatin of chromosomes. C...

Westhorpe(Frederick G),Fuller(Colin J),Str... J Cell Biol 2015-09-10

Centromeres are defined by the presence of CENP-A nucleosomes in chromatin and are essential for accurate chromosome seg...

Elia(Andrew E H),Boardman(Alexander P),Wan... Mol Cell 2015-11-27

...CENPs, underscoring the broad impact of the DDR on cellular physiology.

Baffet(Alexandre D),Hu(Daniel J),Vallee(Ri... Dev Cell 2015-08-28

Dynein recruitment to the nuclear envelope is required for pre-mitotic nucleus-centrosome interactions in nonneuronal ce...

Fachinetti(Daniele),Han(Joo Seok),McMahon(... Dev Cell 2015-09-21

Human centromeres are specified by a stably inherited epigenetic mark that maintains centromere position and function th...

Yu(Zhouliang),Zhou(Xiang),Wang(Wenjing),De... Dev Cell 2015-03-10

The H3 histone variant CENP-A is an epigenetic marker critical for the centromere identity and function. However, the pr...

Lipinszki(Zoltan),Lefevre(Stephane),Savoia... Nat Commun 2015-12-08

The cell division cycle requires tight coupling between protein phosphorylation and dephosphorylation. However, understa...

Ho(Kung-Hsien),Tsuchiya(Dai),Oliger(Audrey... Cell Rep 2015-07-24

In many eukaryotes, the centromere is epigenetically specified and not strictly defined by sequence. In contrast, buddin...

Miell(Matthew D D),Straight(Aaron F) Dev Cell 2015-03-10

In this issue of Developmental Cell, Yu et al. (2015) demonstrate that CENP-A phosphorylation by CDK1 inhibits its assoc...

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