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Cell cycle G2 arrest induced by HIV-1 Vpr in fission yeast (Schizosaccharomyces…

Elder(R T),Yu(M),Chen(M),Edelson(S),Zhao(Y) Virus Res 2000-10-03

...rad17 mutations, which eliminate the G2 checkpoint for DNA damage, did not block the G2 arrest induced by Vpr. Furthermo...

The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1…

Rauen(M),Burtelow(M A),Dufault(V M),Karnitz(… J Biol Chem 2000-11-03

...Rad17 (hRad17) interacts with the PCNA-related checkpoint proteins hRad1, hRad9, and hHus1. Mutational analysis of hRad1...

Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in slid…

Venclovas(C),Thelen(M P) Nucleic Acids Res 2000-09-20

...Rad17(Sp). We have found that these four proteins are conserved with protein sequences throughout eukaryotic evolution. ...

Srs2 DNA helicase is involved in checkpoint response and its regulation require…

Liberi(G),Chiolo(I),Pellicioli(A),Lopes(M),P… EMBO J 2000-11-16

...Rad17 and Rad24. Moreover, DNA damage-induced lethality in rad17 mutants depends partially upon Srs2, suggesting that a ...

Sgs1 helicase activity is required for mitotic but apparently not for meiotic f…

Miyajima(A),Seki(M),Onoda(F),Shiratori(M),Od… Mol Cell Biol 2000-09-21

...RAD17 gene partially alleviated the poor-sporulation phenotype of sgs1 disruptants, indicating that portions of the popu...

The Saccharomyces cerevisiae DNA damage checkpoint is required for efficient re…

de la Torre-Ruiz(M),Lowndes(N F) FEBS Lett 2000-03-31

...RAD17, MEC1, MEC3 and RAD53 checkpoint genes are required for efficient non-homologous end joining (NHEJ). RAD9 and RAD2...

A novel mutant allele of the chromatin-bound fission yeast checkpoint protein R…

Griffiths(D),Uchiyama(M),Nurse(P),Wang(T S) J Cell Sci 2000-05-31

...rad17-d14 was not sensitive to UV irradiation. Interestingly, the ionising radiation sensitivity of rad17-d14 was only a...

Activation of Rad53 kinase in response to DNA damage and its effect in modulati…

Pellicioli(A),Lucca(C),Liberi(G),Marini(F),L… EMBO J 2000-01-20

...Rad17 and Rad24 checkpoint factors, while this dependence is greatly reduced in S phase cells. Furthermore, during recov...

Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replicat…

Shimada(M),Okuzaki(D),Tanaka(S),Tougan(T),Ta… Mol Biol Cell 2000-02-14

...Rad17 in vivo and a significant reduction of the phosphorylated form of Chk1 in rfc3-1 cells after treatments with MMS a...

Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that…

Caspari(T),Dahlen(M),Kanter-Smoler(G),Lindsa… Mol Cell Biol 2000-02-15

...Rad17. We show that Rad17 defines a distinct protein complex in soluble extracts that is separate from Rad1, Rad9, and H...

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