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The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and n…

Ziółkowska-Suchanek(Iwona),Mosor(Maria),Wier… Mol Cancer 2014-07-08

...RAD50 gene.,Our data indicated that previously described common genetic variations in the MRE11 and RAD50 genes do not c...

Sym004, a novel anti-EGFR antibody mixture, augments radiation response in huma…

Huang(Shyhmin),Peet(Chimera R),Saker(Jarob),… Mol Cancer Ther 2014-08-04

...RAD50, and BRCA1. Using single and fractionated radiation in human tumor xenograft models, we confirmed that the combina...

Cause-specific telomere factors deregulation in hepatocellular carcinoma.

El Idrissi(Manale),Hervieu(Valérie),Merle(Ph… J Exp Clin Cancer Res 2014-09-26

...RAD50 non-shelterin telomere factors. For HCV the expression level of POT1, RAP1, Ku80, and RAD50 was higher in cirrhoti...

Defining the contribution of SNPs identified in asthma GWAS to clinical variabl…

Tulah(Asif S),Holloway(John W),Sayers(Ian) BMC Med Genet 2014-01-06

...RAD50 did not show association with any phenotype tested when corrected for multiple testing. Analysis using ENCODE data...

Genome-wide RNAi high-throughput screen identifies proteins necessary for the A…

Solaimani(Parrisa),Damoiseaux(Robert),Hankin… Toxicol Sci 2014-07-01

...RAD50 are required for the expression of AHR as well as for induction of CYP1A1. We also found 2 gene products, ARMC8 an...

Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate ho…

McKerlie(Megan),Walker(John R),Mitchell(Tayl… Nucleic Acids Res 2014-02-13

...Rad50/Nbs1-mediated DNA damage response. While loss of functional BRCA1 impairs the formation of IR-induced (pT371)TRF1 ...

A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independe…

Crown(K Nicole),Savytskyy(Oleksandr P),Malik… G3 (Bethesda) 2014-06-09

Nbs1, a core component of the Mre11-Rad50-Nbs1 complex, plays an essential role in the cellular response to DNA double-s...

A DNA break inducer activates the anticodon nuclease RloC and the adaptive immu…

Klaiman(Daniel),Steinfels-Kohn(Emmanuelle),K… Nucleic Acids Res 2014-02-21

...Rad50 and the antiviral, translation-disabling ACNase PrrC. While PrrC's ACNase is regulated by a DNA restriction-modifi...

Coordination and processing of DNA ends during double-strand break repair: the …

Almond(Joshua R),Stohr(Bradley A),Panigrahi(… Genetics 2014-06-02

The in vivo functions of the bacteriophage T4 Mre11/Rad50 (MR) complex (gp46/47) in double-strand-end processing, double...

Antiproliferative effects of pomegranate extract in MCF-7 breast cancer cells a…

Shirode(Amit B),Kovvuru(Prasad),Chittur(Srid… Mol Carcinog 2014-06-24

...RAD50, NBS1, RAD51, BRCA1, BRCA2, and BRCC3. Downregulation of HR genes correlated with increased levels of their predic...

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