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TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflamm…

Eckfeld(C),Schoeps(B),Häußler(D),Frädrich(J)… J Cell Biol 2023-00-06

...APLP2), which was confirmed by pull-down assays and confocal microscopy. We found that TIMP-1 triggered glucose uptake a...

Diabetes affects AD through plasma Aβ40: A Mendelian randomization study.

Yang(Q),Huang(D),Zhang(Z),Gao(H),Wu(J),Zhong… Neuroscience 2025-05-24

...APLP2. Other diabetic traits may have potential effects on different AD plasma markers.

Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in r…

Richter(MC),Ludewig(S),Winschel(A),Abel(T),B… EMBO J 2018-00-01

...APLP2. APPsα efficiently rescued deficits in spine density, synaptic plasticity (LTP and PPF), and spatial reference mem...

Isolation of genes involved in pancreas regeneration by subtractive hybridizati…

Choi(JH),Lee(MY),Kim(Y),Shim(JY),Han(SM),Lee… Biol Chem 2010-09-00

...Aplp2, Clu, Col1a2, Glul, Krt8, Lgmn, LOC299907, LOC502894, Pla2g1b, Reg3α and Xbp1) were identified, and RT-PCR and rea...

Gene network analysis during early infection of human coronary artery smooth mu…

Nde(PN),Johnson(CA),Pratap(S),Cardenas(TC),K… Chem Biodivers 2010-05-00

...APLP2) as the seed for network construction, we built an interaction network of the early T. cruzi infection process con...

Rapid evolution of mammalian APLP1 as a synaptic adhesion molecule.

Onodera(W),Asahi(T),Sawamura(N) Sci Rep 2021-00-28

...APLP2. Docking simulation identified one positively selected site in APLP1 that alters the heparin-binding site, which c...

A critical function for beta-amyloid precursor protein in neuronal migration re…

Young-Pearse(TL),Bai(J),Chang(R),Zheng(JB),L… J Neurosci 2007-12-26

...APLP2, fully rescued the shRNA-mediated migration defect. Analysis of an array of mutations and deletions in APP reveale...

Analysis of amyloid precursor protein function in Drosophila …

Poeck(B),Strauss(R),Kretzschmar(D) Exp Brain Res 2012-04-00

...APLP2, exist and that knock-out mice for APP only show subtle defects. In contrast, invertebrates like Caenorhabditis ...

Selective localization of amyloid precursor-like protein 1 in the cerebral cort…

Kim(TW),Wu(K),Xu(JL),McAuliffe(G),Tanzi(RE),… Brain Res Mol Brain Res 1995-08-00

...APLP2) have been identified and exhibit extensive sequence similarity to the APPL and APP genes. To define the potential...

Trio-based exome sequencing broaden the genetic spectrum in keratoconus.

Xu(L),Yang(K),Zhu(M),Yin(S),Gu(Y),Fan(Q),Wan… Exp Eye Res 2023-00-00

...APLP2, BCORL1, CCNB3, FOXN1, FUT8, GALNT10, HEPH, HHIP, HMGB3, HS6ST2, JADE3, KIAA0040, MCF2L, MYOF, QRICH2, RPS6KA6, SM...

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