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Multicolor laser scanning confocal immunofluorescence microscopy of DNA damage …

Laubenthal(Julian),Gdula(Michal R),Dhawan(Al… Methods Mol Biol 2014-02-24

...Rad50 as well as phosphorylated H2AX and ATM and in somatic and germ cells as an example.

Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinc…

Regal(Joshua A),Festerling(Todd A),Buis(Jeff… Hum Mol Genet 2014-07-08

...RAD50/NBS1 (MRN) complex binds DSBs and initiates damage-induced signaling cascades via activation of the ataxia-telangi...

Epigenetic interventions increase the radiation sensitivity of cancer cells.

Ren(Juan),Chu(Yongli),Ma(Hongbing),Zhang(Yue… Curr Pharm Des 2014-12-10

...Rad50, and proteins involved in non-homologous end joining (NHEJ) repair pathway which include Ku70, and DNA-PK. HDACs a...

A genome-wide association study of atopic dermatitis identifies loci with overl…

Weidinger(Stephan),Willis-Owen(Saffron A G),… Hum Mol Genet 2014-06-16

...RAD50/IL13 locus on chromosome 5 and the major histocompatibility complex (MHC) on chromosome 6; reflecting action of cl...

Influence of MRE11, RAD50 and NIBRIN protein expression on survival in pancreat…

Horst(Klemens),Ganzera(Silke),Kaisers(Wolfga… Pathol Res Pract 2014-06-04

The MRE11/RAD50/NIBRIN complex, a protein complex that repairs DNA double-strand breaks, could serve as an early marker ...

Antiproliferative effects of pomegranate extract in MCF-7 breast cancer cells a…

Shirode(Amit B),Kovvuru(Prasad),Chittur(Srid… Mol Carcinog 2014-06-24

...RAD50, NBS1, RAD51, BRCA1, BRCA2, and BRCC3. Downregulation of HR genes correlated with increased levels of their predic...

Sak1 kinase interacts with Pso2 nuclease in response to DNA damage induced by i…

Munari(Fernanda M),Revers(Luis F),Cardone(Ja… J Photochem Photobiol B 2014-11-13

...RAD50, PSO2 and XRS2 genes in 8-MOP+UVA treated exponentially growing cells.

The essential function of the MRN complex in the resolution of endogenous repli…

Bruhn(Christopher),Zhou(Zhong-Wei),Ai(Haiyan… Cell Rep 2014-09-25

...Rad50/Nbs1) is important in double-strand break (DSB) recognition, end resection, replication fork stabilization, and AT...

Exome sequencing reveals a novel MRE11 mutation in a patient with progressive m…

Miyamoto(Ryosuke),Morino(Hiroyuki),Yoshizawa… J Neurol Sci 2014-10-06

...RAD50 and NBS1) via Western blot, and they were markedly decreased compared to a healthy control. Mutations in the MRE11...

Coordination and processing of DNA ends during double-strand break repair: the …

Almond(Joshua R),Stohr(Bradley A),Panigrahi(… Genetics 2014-06-02

The in vivo functions of the bacteriophage T4 Mre11/Rad50 (MR) complex (gp46/47) in double-strand-end processing, double...

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