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Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain w…

Dahms(SO),Mayer(MC),Roeser(D),Multhaup(G),Th… Acta Crystallogr D Biol Cryst… 2015-03-00

...APLP2) contain the highly conserved heparan sulfate (HS) binding domain E2, which effects various (patho)physiological f...

Nicotine-induced protein expression profiling reveals mutually altered proteins…

Paulo(JA),Gygi(SP) Proteomics 2017-00-00

...APLP2, LAPTM4B, and NCOA4, which were dysregulated by nicotine in all cell lines investigated and may have implications ...

Novel Insights into the Physiological Function of the APP (Gene) Family and Its…

Ludewig(S),Korte(M) Front Mol Neurosci 2016-00-00

...APLP2 and APP are functionally redundant, the exclusively CNS expressed APLP1, might have individual roles within the sy...

Familial Alzheimer's disease mutations in amyloid precursor protein impair calc…

Tavalin(SJ) J Biol Chem 2025-02-00

...APLP2, respectively). Electrophysiological analysis demonstrates that APP and its family members limit NMDAR activity, i...

Isobaric Tag-Based Protein Profiling of a Nicotine-Treated Alpha7 Nicotinic Rec…

Paulo(JA),Gygi(SP) Proteomics 2018-00-00

...APLP2, and ITM2B. The magnitude of these changes was greater in HAP1wt compared to the α7KO-HAP1 cell line, implying a p...

The impact of genetic variants in folliculogenesis and steroidogenesis pathways…

Neves(AR),Casarini(L),Carretta(C),Manfredini… J Assist Reprod Genet 2025-12-00

...APLP2 (rs2054247), AP4E1 (rs4775912), SMARCA4 (rs1122608), IGF1R (rs2016347), DENND1A (rs2479106), and BMP15 (rs3897937)...

UV irradiation accelerates amyloid precursor protein (APP) processing and disru…

Almenar-Queralt(A),Falzone(TL),Shen(Z),Lillo… J Neurosci 2014-02-26

...APLP2 decline by accelerating their secretase-dependent processing. Pharmacological inhibition of endosomal/lysosomal ac...

Upregulation of APP, ADAM10 and ADAM17 in the denervated mouse dentate gyrus.

Del Turco(D),Schlaudraff(J),Bonin(M),Deller(… PLoS One 2014-00-00

...Aplp2) in the dentate gyrus of the mouse following entorhinal denervation. Using laser microdissection, tissue was harve...

Transcriptome profiling of morphogenetic differences between contour and flight…

Xu(Q),Xi(Y),Ma(S),Wang(J),Li(J),Han(C),Li(L)… Br Poult Sci 2022-10-00

...APLP2 (in another module) may be essential candidate genes for influencing feather morphology. Moreover, seven transcrip...

Identification and regulation of the high affinity binding site of the Alzheime…

Multhaup(G) Biochimie 1994-00-00

...APLP2, was identified. Saturable binding to heparin through this binding site was found to occur at nmol concentrations ...

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