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Histone modifications rather than the novel regional centromeres of Zymosepto...

Schotanus(Klaas),Soyer(Jessica L),Connolly... Epigenetics Chromatin 2015-10-02

Supernumerary chromosomes have been found in many organisms. In fungi, these "accessory" or "dispensable" chromosomes ar...

Expression data of HeLa cells treated with CENP-E siRNA or Eg5 siRNA in the p...

Nakayama(Yusuke),Ohashi(Akihiro) Genom Data 2015-12-23

The molecular mechanism responsible for cell fate after mitotic slippage is unclear. We investigated the postmitotic eff...

Atypical centromeres in plants-what they can tell us.

Cuacos(Maria),H Franklin(F Chris),Heckmann... Front Plant Sci 2015-11-20

The centromere, visible as the primary constriction of condensed metaphase chromosomes, is a defined chromosomal locus e...

Overexpression of centromere protein K (CENPK) in ovarian cancer is correlate...

Lee(Yi-Chao),Huang(Chi-Chen),Lin(Ding-Yen)... PeerJ 2015-11-20

Ovarian cancer has a poor prognosis. Most patients are diagnosed with ovarian cancer when the disease has reached an adv...

Differential distribution of HP1 proteins after trichostatin a treatment infl...

González-Barrios(Rodrigo),Soto-Reyes(Ernes... Cell Div 2015-03-02

Heterochromatin protein 1 (HP1) is important in the establishment, propagation, and maintenance of constitutive heteroch...

Pgp efflux pump decreases the cytostatic effect of CENP-E inhibitor GSK923295...

Tcherniuk(Sergey O),Oleinikov(Andrew V) Cancer Lett 2015-05-21

Human kinesin CENP-E is an attractive target for cancer chemotherapy. The allosteric CENP-E inhibitor GSK923295 was prop...

CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromer...

Niikura(Yohei),Kitagawa(Risa),Ogi(Hiroo),A... Dev Cell 2015-05-07

CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity to ensure kinetoch...

Both tails and the centromere targeting domain of CENP-A are required for cen...

Logsdon(Glennis A),Barrey(Evelyne J),Basse... J Cell Biol 2015-04-28

The centromere-defined by the presence of nucleosomes containing the histone H3 variant, CENP-A-is the chromosomal locus...

Mammalian Polo-like kinase 1 (Plk1) promotes proper chromosome segregation by...

Park(Chi Hoon),Park(Jung-Eun),Kim(Tae-Sung... J Biol Chem 2015-06-02

Mammalian Plk1 is critically required for proper M phase progression. Plk1 is self-recruited to prekinetochores/kinetoch...

Genetic and epigenetic regulation of centromeres: a look at HAC formation.

Ohzeki(Jun-ichirou),Larionov(Vladimir),Ear... Chromosome Res 2015-12-14

The centromere is a specialized chromosomal locus required for accurate chromosome segregation. A specific histone H3 va...

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