Supernumerary chromosomes have been found in many organisms. In fungi, these "accessory" or "dispensable" chromosomes ar...
The molecular mechanism responsible for cell fate after mitotic slippage is unclear. We investigated the postmitotic eff...
The centromere, visible as the primary constriction of condensed metaphase chromosomes, is a defined chromosomal locus e...
Ovarian cancer has a poor prognosis. Most patients are diagnosed with ovarian cancer when the disease has reached an adv...
Heterochromatin protein 1 (HP1) is important in the establishment, propagation, and maintenance of constitutive heteroch...
Human kinesin CENP-E is an attractive target for cancer chemotherapy. The allosteric CENP-E inhibitor GSK923295 was prop...
CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity to ensure kinetoch...
The centromere-defined by the presence of nucleosomes containing the histone H3 variant, CENP-A-is the chromosomal locus...
Mammalian Plk1 is critically required for proper M phase progression. Plk1 is self-recruited to prekinetochores/kinetoch...
The centromere is a specialized chromosomal locus required for accurate chromosome segregation. A specific histone H3 va...
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