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G2/M checkpoint genes of Saccharomyces cerevisiae: further evidence for roles i…

Lydall(D),Weinert(T) Mol Gen Genet 1998-02-13

We have cloned, sequenced and disrupted the checkpoint genes RAD17, RAD24 and MEC3 of Saccharomyces cerevisiae. Mec3p sh...

RAD9 and RAD24 define two additive, interacting branches of the DNA damage chec…

de la Torre-Ruiz(M A),Green(C M),Lowndes(N F) EMBO J 1998-06-18

In budding yeast, RAD9 and RAD24/RAD17/MEC3 are believed to function upstream of MEC1 and RAD53 in signalling the presen...

Identification of a human homologue of the Schizosaccharomyces pombe rad17+ che…

Parker(A E),Van de Weyer(I),Laus(M C),Verhas… J Biol Chem 1998-08-13

...rad17+ checkpoint gene, designated Hrad17. Hrad17 has 49% identity to the S. pombe rad17+ sequence at the DNA level and ...

Cdc20, a beta-transducin homologue, links RAD9-mediated G2/M checkpoint control…

Lim(H H),Surana(U) Mol Gen Genet 1997-02-12

...RAD17, RAD24, MEC1, MEC2 and MEC3. These genes also prevent entry into mitosis of a temperature-sensitive mutant, cdc13,...

RAD9, RAD17, and RAD24 are required for S phase regulation in Saccharomyces cer…

Paulovich(A G),Margulies(R U),Garvik(B M),Ha… Genetics 1997-04-08

...RAD17, RAD24) involved in the DNA damage checkpoint pathway also play a role in regulating S phase in response to DNA da...

Distinct roles of yeast MEC and RAD checkpoint genes in transcriptional inducti…

Kiser(G L),Weinert(T A) Mol Biol Cell 1997-03-07

...RAD17 mediates but a single pathway. The three other checkpoint genes (including RAD9) have small (twofold) but signific...

Yeast checkpoint genes in DNA damage processing: implications for repair and ar…

Lydall(D),Weinert(T) Science 1996-01-04

...RAD17, RAD24, and MEC3 activated an exonuclease that degrades DNA. The degradation is probably a direct consequence of c...

The chk1 pathway is required to prevent mitosis following cell-cycle arrest at …

Carr(A M),Moudjou(M),Bentley(N J),Hagan(I M) Curr Biol 1996-02-22

...Rad17, a typical example of a rad gene product.,Genetic dissection of checkpoints in logarithmically growing fission yea...

Cloning and characterization of RAD17, a gene controlling cell cycle responses …

Siede(W),Nusspaumer(G),Portillo(V),Rodriguez… Nucleic Acids Res 1996-07-25

...RAD17 gene by complementation of the UV sensitivity of a rad17-1 mutant and identified an ORF of 1.2 kb encoding a predi...

A meiotic recombination checkpoint controlled by mitotic checkpoint genes.

Lydall(D),Nikolsky(Y),Bishop(D K),Weinert(T) Nature 1996-12-02

...RAD17, RAD24 and MEC1 ensures that meiotic recombination is complete before the first meiotic division (MI). First, RAD1...

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