We have cloned, sequenced and disrupted the checkpoint genes RAD17, RAD24 and MEC3 of Saccharomyces cerevisiae. Mec3p sh...
In budding yeast, RAD9 and RAD24/RAD17/MEC3 are believed to function upstream of MEC1 and RAD53 in signalling the presen...
...rad17+ checkpoint gene, designated Hrad17. Hrad17 has 49% identity to the S. pombe rad17+ sequence at the DNA level and ...
...RAD17, RAD24, MEC1, MEC2 and MEC3. These genes also prevent entry into mitosis of a temperature-sensitive mutant, cdc13,...
...RAD17, RAD24) involved in the DNA damage checkpoint pathway also play a role in regulating S phase in response to DNA da...
...RAD17 mediates but a single pathway. The three other checkpoint genes (including RAD9) have small (twofold) but signific...
...RAD17, RAD24, and MEC3 activated an exonuclease that degrades DNA. The degradation is probably a direct consequence of c...
...Rad17, a typical example of a rad gene product.,Genetic dissection of checkpoints in logarithmically growing fission yea...
...RAD17 gene by complementation of the UV sensitivity of a rad17-1 mutant and identified an ORF of 1.2 kb encoding a predi...
...RAD17, RAD24 and MEC1 ensures that meiotic recombination is complete before the first meiotic division (MI). First, RAD1...
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