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Emerging role of DNA polymerase epsilon non-exonuclease domain mutations in c...

Xu(JJ),Ni(CX),Xu(JJ) World J Gastroenterol 2026-02-14

...BRAF, implying a potential synergistic interaction between impaired DNA repair mechanisms and activation of oncogenic pa...

Hepatic carcinosarcoma: a rare and aggressive case with unusual molecular sig...

Almahari(SA),Al-Ani(M),Zaitoun(AM),Gordon(... Front Oncol None

...BRAF fusion alongside oncogenic variants: TERT c.-124C>T (VAF 0.60) and TP53 c.811G>A p. (Glu271Lys) (VAF 0.90). Targete...

Immune checkpoint inhibitor in third-line treatment of microsatellite stable ...

Zhao(Q),Zhao(K),Song(J),Zhao(W) BMC Cancer 2026-02-16

...BRAF could obtain PFS benefit from third-line ICI over non-ICI treatment. Thirty-six (38.7%) patients developed at least...

Establishment and characterization of a cell line (OS-MM) originating from a ...

Shintani(T),Hamada(A),Yamasaki(S),Jono(Y),... In Vitro Cell Dev Biol Anim 2026-05-00

...BRAF and NRAS mutations; however, a GNAS mutation was identified. The OS-MM cell line should contribute to advances in p...

End‑of‑life care in advanced melanoma: a retrospective cohort study from an I...

De Mattia(M),Boutros(A),Delucchi(V),Blonde... BMC Cancer 2026-02-21

...BRAF-mutant melanoma, 33 (72%) received BRAF/MEK inhibitors. At three months before death, 80 (86%) patients remained on...

Mutational status of non-invasive follicular thyroid neoplasm with papillary-...

Sako(A),Hirokawa(M),Matsuse(M),Higuchi(M),... J Pathol Transl Med 2026-03-00

...BRAFV600E mutation, particularly for NS3 tumors. We performed genetic analysis on 92 archival thyroid tumor samples, inc...

Transoral videolaryngoscopic surgery for hypopharyngeal anaplastic metastasis...

Yokoyama(Y),Nishio(N),Sugiura(M),Suzuki(K)... JCEM Case Rep 2026-02-00

...BRAF V600E pathogenic variant, leading to treatment with encorafenib and binimetinib, initiated on postoperative day 24....

The risk of radiation necrosis from combined radiotherapy and BRAF inhibitor ...

Yang(L),He(Y),Peng(Y),Sun(M),Tang(Z),Du(L)... Front Oncol None

...BRAF-V600E mutations emerge as a resistance mechanism to EGFR tyrosine kinase inhibitors. While the combination of BRAF/...

BRAF and MEK inhibition beyond dabrafenib-trametinib in advanced thyroid canc...

Yamin(T),Cohen(O),Robenshtok(E),Izkhakov(E... Front Endocrinol (Lausanne) None

...BRAF and MEK inhibitors. All patients had confirmed BRAF V600E mutation. Among three patients treated with BRAF/MEK inhi...

Matched tissue-blood whole-exome sequencing improves detection of genetic eti...

Ruan(Y),Chen(L),Xia(S),Lu(Q),Wang(J),Zhu(F... Front Pediatr None

...BRAF variants were detected in the diseased brain tissue, with mosaic levels of 20.2% and 13.5%, respectively. Matched t...

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