Centromeres ensure chromosome segregation, but their chromatin organization within repetitive alpha-satellite DNA has be...
We present telomere-to-telomere genome assemblies of a Thoroughbred horse and a donkey derived from their mule offspring...
Centromere identity is specified by CENP-A, a histone H3 variant that epigenetically defines centromere position. How CE...
Objective: Patients with systemic lupus erythematosus (SLE) exhibit elevated malignancy risk, with increased bladder can...
Accurate segregation of mitotic chromosomes requires pre-anaphase alignment driven by microtubule-based motor proteins. ...
Chromosome segregation in eukaryotes requires the orchestrated interaction of chromosomes with microtubules, mediated by...
Centromeres are specialized chromatin structures essential for equal chromosome segregation. The human centromeres are o...
Chromatin organization plays a fundamental role in the regulation and preservation of the eukaryotic genome. Histone var...
Centromere protein A (CENP-A), a centromeric histone H3 variant highly expressed in aggressive cancers, promotes epithel...
Each chromosome contains a centromere, the site at which the kinetochore assembles to ensure accurate chromosome segrega...
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