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A dCas9-integrated iLight9O system enables dynamic regulation for enhanced pa...

Li(L),Wang(Y),Wang(B),Shen(L),Gao(Y),Lin(W... Bioresour Technol 2026-04-00

...CRISPR-dCas9 platform. The stability of the iLight9 system was further enhanced by employing a strategy involving the ad...

Growth hormone enhances mitochondria biogenesis and endows mitochondrial ther...

Sadiq(E),Liu(Y),Li(N),Zong(C),Li(X),Yu(T),... Mol Cell Endocrinol 2026-06-00

...CRISPR-Cas9 technique. We therefore conclude that GH has effects on reducing adipocyte size via promoting PGC1α and POLG...

Unlocking the potential of functional food polysaccharides: The zebrafish mod...

Liu(Y),Che(S),Xu(J),Guo(Y) Carbohydr Polym 2026-04-15

...CRISPR will further enhance mechanistic studies. We conclude that zebrafish are a cost-effective and efficient tool for ...

Highly fluorescent copper nanoclusters as programmable reporters for CRISPR/C...

Carota(AG),Spiaggia(F),Poma(N),Palladino(P... Biosens Bioelectron 2026-05-15

...CRISPR/Cas12a system to achieve programmable and highly specific target recognition. Upon target binding, activation of ...

The chaperonin TRiC component Cct3 is required for axonal transport, myelinat...

Zhang(X),Zajt(KK),Palaz(T),Wang(L),Groß(M)... Cell Death Dis 2026-02-12

...CRISPR/Cas9 loss-of-function alleles of the orthologous zebrafish cct3 gene. By combining these alleles with transgenic ...

PRICE: direct and robust detection of microRNAs at single-nucleotide resolution.

Wang(B),Zhou(S),Zhang(X),Wang(R),Huang(S),... Nat Commun 2026-02-12

...CRISPR/Cas13a system (PRICE), enabling detection of SNVs in miRNA sequence without sacrificing the sensitivity. PRICE ut...

Targeted elimination of Staphylococcus aureus mastitis infections with synthe...

Garmendia-Antoñana(N),Dorado-Morales(P),Gi... NPJ Biofilms Microbiomes 2026-02-12

...CRISPR-Cas9 modules targeting small RNA genes. ePICIs exhibit bactericidal activity without chromosomal integration, an ...

Effect of a truncated mutant factor V on hemostatic function and embryonic de...

Miguel-Batuecas(A),De Pablo-Moreno(JA),Por... Sci Rep 2026-02-12

...CRISPR-engineered mouse model intended to produced a mild factor V deficiency disease, unexpectedly produced a frameshif...

Modular engineering of thermoresponsive allosteric proteins.

Kroell(AS),Hoffmann(KH),Motzkus(NA),Lemmen... Nat Chem Biol 2026-05-00

...CRISPR-Cas genome editors directly modulated by subtle temperature changes within the physiological range. Lastly, we sh...

TRPV2 regulates cell fate in the human granulosa-like tumor cell line KGN: im...

Eubler(K),Jeevanandan(SP),Caban(KM),Stöckl... Cell Commun Signal 2026-02-12

...CRISPR/Cas9-based deletion of TRPV2 on cell proliferation, migration and macropinocytotic behavior, examined changes in ...

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