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First-Line Treatment of Advanced Thoracic SMARCA4-Deficient Undifferentiated ...

Wen(Q),Long(M),Li(F),Peng(Y),Yi(J),Wu(Y),W... Case Rep Oncol Med None

...SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) of the chest is a highly aggressive smoking-related thoracic malig...

Clinical and Pathological Characteristics of Stage IV SMARCA4-Deficient Lung ...

Ma(J),Deng(M),Xu(X),Hou(Y),He(J) Clin Oncol (R Coll Radiol) 2026-04-00

...SMARCA4 deficiency and 216 (75.5%) with SMARCA4 proficiency. Patients who completed two or more cycles of systemic thera...

Case Report: A successfully managed case of SMARCA4-deficient undifferentiate...

Peng(R),Shi(Y),Wu(P),Chen(J),Li(G) Front Oncol None

We report a case of SMARCA4-deficient poorly-to-undifferentiated gastric carcinoma. The patient underwent surgical resec...

A Rare SMARCA4-Deficient Subglottic Adenoid Cystic Carcinoma With Early Pulmo...

Fang(KC),Fang(FM),Li(SH),Chien(CY) Laryngoscope 2026-08-00

...SMARCA4 loss-of-function mutation, a molecular driver not previously reported in this anatomical site. Despite presentin...

SMARCA4-deficient thoracic malignancies with small cell lung cancer-like feat...

Ding(JR),Li(XG),Wang(X),Cheng(K),Xia(QY),X... Ann Diagn Pathol 2026-08-00

...SMARCA4 mutation with complete loss of SMARCA4 protein expression, yet fell into distinct diagnostic categories: Case 1,...

Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-bas...

Wang(Z),He(X),Zhang(X),Spiegel(J),Flynn(SM... Nat Chem 2026-06-00

...SMARCA4 and ATRX. These proteins are important therapeutic targets that play crucial roles in transcription regulation a...

Uncovering the metabolic-epigenetic links between gene expression and stroke:...

Kan(J),Hong(Y),Min(R),Zhang(B),Wang(H) Neurol Res Pract 2026-03-24

...SMARCA4, STMN1, and LDHA was significantly associated with increased risk of IS or its subtypes. In contrast, SLC16A1, S...

Emerging Predictive Biomarkers of Immunotherapy Sensitivity in Patients with ...

Gariazzo(E),Colamartini(F),Ubaldi(M),Santo... Immunotargets Ther None

...SMARCA4), markers of metabolic pathway dysregulation (IDO, adenosine axis), tumor-infiltrating lymphocytes, and blood-ba...

The SMARCA4-TMEM47 axis plays an essential role in chikungunya virus RNA repl...

Fu(YZ),Luo(FF),Yang(L),Li(JY),Zhang(BW),Li... Proc Natl Acad Sci U S A 2026-03-24

...SMARCA4 as a host factor for CHIKV. SMARCA4 acts as a chromatin remodeling factor to license expression of the four-pass...

Dual PD-1/IL-2Rα targeting restores CD8+ T cell fitness via STAT5/CD47 axis i...

Shang(X),Cheng(B),Li(Z),Wang(H),Zhang(C),T... Cell Rep Med 2026-03-17

SMARCA4-deficient non-small cell lung cancer (NSCLC) is a genomically distinct and clinically aggressive subtype charact...

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