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Kaczmarczyk(Agnieszka),Sullivan(Kevin F) PLoS One 2015-06-29

The CENP-W/T complex was previously reported to be required for mitosis. HeLa cells depleted of CENP-W displayed profoun...

Wen(Yan),Zhao(Shuqin),Chao(Lan),Yu(Honglin... Cryobiology 2015-05-18

Several studies have reported the oocyte damage in mice during vitrification; however, little has been known about the p...

Bloom(Kerry S) Annu Rev Genet 2015-07-08

Centromeres are specialized domains of heterochromatin that provide the foundation for the kinetochore. Centromeric hete...

Wu(Qing),Chen(Yong-Feng),Fu(Jie),You(Qi-Ha... Cell Oncol (Dordr) 2015-09-15

Deregulation of centromere protein (CENP)-A, a centromere-specific histone variant, has in the past been linked to cance...

Erliandri(Indri),Fu(Haiqing),Nakano(Megumi... Nucleic Acids Res 2015-01-15

In human chromosomes, centromeric regions comprise megabase-size arrays of 171 bp alpha-satellite DNA monomers. The larg...

Wielosz(Ewa),Dryglewska(Magdalena),Majdan(... Postepy Hig Med Dosw (Onlin... 2015-06-26

The systemic sclerosis-associated autoantibodies include anti-centromere, anti-topoisomerase I (anti-topo I), anti-RNA p...

Barisic(Marin),Aguiar(Paulo),Geley(Stephan... Nat Cell Biol 2015-03-10

Accurate chromosome segregation during cell division in metazoans relies on proper chromosome congression at the equator...

Macchia(Gemma),Nord(Karolin H),Zoli(Monica... Genes Chromosomes Cancer 2015-09-23

Gene amplification is relatively common in tumors. In certain subtypes of sarcoma, it often occurs in the form of ring a...

Arimura(Yasuhiro),Shirayama(Kazuyoshi),Hor... Sci Rep 2015-10-19

The centromere-specific histone H3 variant, CENP-A, is overexpressed in particular aggressive cancer cells, where it can...

Bancroft(James),Auckland(Philip),Samora(Ca... J Cell Sci 2015-07-14

A key step of mitosis is the congression of chromosomes to the spindle equator. Congression is driven by at least two di...