Deregulation of centromere protein (CENP)-A, a centromere-specific histone variant, has in the past been linked to cance...
In human chromosomes, centromeric regions comprise megabase-size arrays of 171 bp alpha-satellite DNA monomers. The larg...
The systemic sclerosis-associated autoantibodies include anti-centromere, anti-topoisomerase I (anti-topo I), anti-RNA p...
Centromeres are specialized domains of heterochromatin that provide the foundation for the kinetochore. Centromeric hete...
Human T-cell leukaemia virus type-1 (HTLV-1) infection causes adult T-cell leukaemia (ATL). The viral protein HTLV-1 bZI...
The centromere is a specific chromosomal locus that organizes the assembly of the kinetochore. It plays a fundamental ro...
Several studies have reported the oocyte damage in mice during vitrification; however, little has been known about the p...
Centromere protein F (CENP-F), a cell cycle-regulated centromere protein, has been shown to affect numerous tumorigenic ...
Centromere-associated protein-E (CENP-E), a mitotic kinesin that plays an important role in mitotic progression, is an a...
Suppression of cell proliferation by targeting mitosis is one potential cancer intervention. A number of existing chemot...
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