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Serological profile of patients with systemic sclerosis.

Wielosz(Ewa),Dryglewska(Magdalena),Majdan(Ma… Postepy Hig Med Dosw (Online) 2015-06-26

The systemic sclerosis-associated autoantibodies include anti-centromere, anti-topoisomerase I (anti-topo I), anti-RNA p...

Kinetochore motors drive congression of peripheral polar chromosomes by overcom…

Barisic(Marin),Aguiar(Paulo),Geley(Stephan),… Nat Cell Biol 2015-03-10

Accurate chromosome segregation during cell division in metazoans relies on proper chromosome congression at the equator...

Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas.

Macchia(Gemma),Nord(Karolin H),Zoli(Monica),… Genes Chromosomes Cancer 2015-09-23

Gene amplification is relatively common in tumors. In certain subtypes of sarcoma, it often occurs in the form of ring a...

Crystal structure and stable property of the cancer-associated heterotypic nucl…

Arimura(Yasuhiro),Shirayama(Kazuyoshi),Horik… Sci Rep 2015-10-19

The centromere-specific histone H3 variant, CENP-A, is overexpressed in particular aggressive cancer cells, where it can...

Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways.

Bancroft(James),Auckland(Philip),Samora(Cata… J Cell Sci 2015-07-14

A key step of mitosis is the congression of chromosomes to the spindle equator. Congression is driven by at least two di...

The CENP-O complex requirement varies among different cell types.

Kagawa(Naoko),Hori(Tetsuya),Hoki(Yuko),Hosoy… Chromosome Res 2015-09-21

CENP-U (CENP-50) is a component of the CENP-O complex, which includes CENP-O, CENP-P, CENP-Q, CENP-R, and CENP-U and is ...

HTLV-1 bZIP factor suppresses the centromere protein B (CENP-B)-mediated trimet…

Mukai(Risa),Ohshima(Takayuki) J Gen Virol 2015-03-30

Human T-cell leukaemia virus type-1 (HTLV-1) infection causes adult T-cell leukaemia (ATL). The viral protein HTLV-1 bZI...

Ectopic centromere nucleation by CENP--a in fission yeast.

Gonzalez(Marlyn),He(Haijin),Dong(Qianhua),Su… Genetics 2015-07-23

The centromere is a specific chromosomal locus that organizes the assembly of the kinetochore. It plays a fundamental ro...

The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromere…

Mérai(Zsuzsanna),Chumak(Nina),García-Aguilar… Proc Natl Acad Sci U S A 2015-04-14

Centromeres mediate chromosome segregation and are defined by the centromere-specific histone H3 variant (CenH3)/centrom...

Repetitive centromeric satellite RNA is essential for kinetochore formation and…

Rošić(Silvana),Köhler(Florian),Erhardt(Sylvi… J Cell Biol 2015-01-06

Chromosome segregation requires centromeres on every sister chromatid to correctly form and attach the microtubule spind...

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