The systemic sclerosis-associated autoantibodies include anti-centromere, anti-topoisomerase I (anti-topo I), anti-RNA p...
Accurate chromosome segregation during cell division in metazoans relies on proper chromosome congression at the equator...
Gene amplification is relatively common in tumors. In certain subtypes of sarcoma, it often occurs in the form of ring a...
The centromere-specific histone H3 variant, CENP-A, is overexpressed in particular aggressive cancer cells, where it can...
A key step of mitosis is the congression of chromosomes to the spindle equator. Congression is driven by at least two di...
CENP-U (CENP-50) is a component of the CENP-O complex, which includes CENP-O, CENP-P, CENP-Q, CENP-R, and CENP-U and is ...
Human T-cell leukaemia virus type-1 (HTLV-1) infection causes adult T-cell leukaemia (ATL). The viral protein HTLV-1 bZI...
The centromere is a specific chromosomal locus that organizes the assembly of the kinetochore. It plays a fundamental ro...
Centromeres mediate chromosome segregation and are defined by the centromere-specific histone H3 variant (CenH3)/centrom...
Chromosome segregation requires centromeres on every sister chromatid to correctly form and attach the microtubule spind...
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