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TP53 BRCA1 CRISPR single-cell cancer

Gonzalez(Marlyn),He(Haijin),Dong(Qianhua),Su… Genetics 2015-07-23

The centromere is a specific chromosomal locus that organizes the assembly of the kinetochore. It plays a fundamental ro...

Wen(Yan),Zhao(Shuqin),Chao(Lan),Yu(Hongling)… Cryobiology 2015-05-18

Several studies have reported the oocyte damage in mice during vitrification; however, little has been known about the p...

Mi(Y-J),Gao(J),Xie(J-D),Cao(J-Y),Cui(S-X),Ga… Dis Esophagus 2014-03-26

Centromere protein F (CENP-F), a cell cycle-regulated centromere protein, has been shown to affect numerous tumorigenic ...

Hirayama(Takaharu),Okaniwa(Masanori),Imada(T… Bioorg Med Chem 2014-03-18

Centromere-associated protein-E (CENP-E), a mitotic kinesin that plays an important role in mitotic progression, is an a...

Salmela(Anna-Leena),Kallio(Marko J) Chromosoma 2014-03-26

Suppression of cell proliferation by targeting mitosis is one potential cancer intervention. A number of existing chemot...

Castillo(Araceli G),Pidoux(Alison L),Catania… PLoS One 2014-04-21

The histone H3 variant, CENP-A, is normally assembled upon canonical centromeric sequences, but there is no apparent obl...

Bee(Leonardo),Fabris(Sonia),Cherubini(Robert… PLoS One 2014-04-17

This study investigated the efficiency of Non-Homologous End Joining (NHEJ) and Homologous Recombination (HR) repair sys...

Maresca(Thomas J) Curr Biol 2014-05-16

Localization of the histone H3 variant Cse4 (CENP-A) at the ~125 base pair point centromere in budding yeast directs ass...

Weng(Meng-Tzu),Luo(Ji) Protein Cell 2014-06-02

Enhancer of rudimentary homolog (ERH) is a small, highly conserved protein among eukaryotes. Since its discovery nearly ...

Silk(Alain D),Zasadil(Lauren M),Holland(Andr… Proc Natl Acad Sci U S A 2014-01-08

Aneuploidy, a chromosome content other than a multiple of the haploid number, is a common feature of cancer cells. Whole...

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