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Transcription and ncRNAs: at the cent(rome)re of kinetochore assembly and maint…

Scott(Kristin C) Chromosome Res 2014-07-07

Centromeres are sites of chromosomal spindle attachment during mitosis and meiosis. Centromeres are defined, in part, by...

MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic re…

Bhattacharjee(Sonali),Osman(Fekret),Feeney(L… Open Biol 2014-03-18

The histone-fold proteins Mhf1/CENP-S and Mhf2/CENP-X perform two important functions in vertebrate cells. First, they a...

Epigenetically induced paucity of histone H2A.Z stabilizes fission-yeast ectopi…

Ogiyama(Yuki),Ohno(Yuko),Kubota(Yoshino),Ish… Nat Struct Mol Biol 2014-02-24

In most eukaryotes, centromeres are epigenetically defined by nucleosomes that contain the histone H3 variant centromere...

Transfer of Ser7 phosphorylated CENP-A from centromere to midbody during mitosi…

Liu(R-M),Tian(X-Y),Huang(X-T),Zhou(H) Folia Biol (Praha) 2014-08-25

Serine 7 of centromere protein A (CENP-A) is a very important mitosis-specific phosphorylation site. In this study, we d...

Lateral to end-on conversion of chromosome-microtubule attachment requires kine…

Shrestha(Roshan L),Draviam(Viji M) Curr Biol 2014-04-22

Proper attachment of chromosomes to microtubules is crucial for the accurate segregation of chromosomes. Human chromosom...

Overexpression of CENP-H as a novel prognostic biomarker for human hepatocellul…

Lu(Guifang),Shan(Tao),He(Shuixiang),Ren(Muda… Oncol Rep 2014-04-07

Centromere protein H (CENP-H) has been shown to be significantly upregulated in many types of cancers and is associated ...

Distinct modes of centromere protein dynamics during cell cycle progression in …

Lidsky(Peter V),Sprenger(Frank),Lehner(Chris… J Cell Sci 2014-07-14

Centromeres are specified epigenetically in animal cells. Therefore, faithful chromosome inheritance requires accurate m...

Comprehensive analysis of LANA interacting proteins essential for viral genome …

Verma(Subhash C),Cai(Qiliang),Kreider(Edward… PLoS One 2014-07-01

Kaposi's sarcoma associated herpesvirus is tightly linked to multiple human malignancies including Kaposi's sarcoma (KS)...

An Iml3-Chl4 heterodimer links the core centromere to factors required for accu…

Hinshaw(Stephen M),Harrison(Stephen C) Cell Rep 2014-07-21

Accurate segregation of genetic material in eukaryotes relies on the kinetochore, a multiprotein complex that connects c...

Neocentromeres: a place for everything and everything in its place.

Scott(Kristin C),Sullivan(Beth A) Trends Genet 2014-07-18

Centromeres are essential for chromosome inheritance and genome stability. Centromeric proteins, including the centromer...

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