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Impaired DNA double-strand break repair contributes to the age-associated rise …

Li(Z),Zhang(W),Chen(Y),Guo(W),Zhang(J),Tang(… Cell Death Differ 0000-00-00

...Rad51, do not change in expression level with age, but Rad51 exhibits a slow kinetics of recruitment to DNA damage sites...

Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination I…

Keyamura(Kenji),Arai(Kota),Hishida(Takashi) PLoS Genet 0000-00-00

...Rad51 or deleting the Rad51-interaction domain of Srs2, whereas phosphorylation and sumoylation of Srs2 and its interact...

HP1 regulates the localization of FANCJ at sites of DNA double-strand breaks.

Wu(Wenwen),Togashi(Yukiko),Johmura(Yoshikazu… Cancer Sci 0000-00-00

...RAD51 and sister chromatid exchange were only inhibited by HP1 depletion or disruption of the BARD1-HP1 interaction. Tak...

Rad51 Nucleoprotein Filament Disassembly Captured Using Fluorescent Plasmodium …

Davenport(Eric Parker),Harris(Derek F),Origa… PLoS One 0000-00-00

...Rad51 nucleoprotein filaments by the Srs2 helicase during HR. Our studies provide a rate for the disassembly of the Rad5...

Homologous recombination-dependent repair of telomeric DSBs in proliferating hu…

Mao(Pingsu),Liu(Jingfan),Zhang(Zepeng),Zhang… Nat Commun 0000-00-00

...Rad51. These findings reveal proliferation-dependent DSBR in telomeres and suggest that telomeric HR, which is normally ...

Temporal and Spatial Uncoupling of DNA Double Strand Break Repair Pathways with…

Tsouroula(Katerina),Furst(Audrey),Rogier(Mel… Mol Cell 0000-00-00

...RAD51. This is independent of chromatin relaxation but requires end resection and RAD51 exclusion from the core. DSBs th...

The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide re…

Ye(Yanfang),Kirkham-McCarthy(Lucy),Lahue(Rob… DNA Repair (Amst) 0000-00-00

...Rad51 had only a minor effect. Coupled with previous evidence, this suggests that MRX drives expansions of short TNRs th...

135G/C polymorphism in the RAD51 gene and acute myeloid leukemia risk: a meta-a…

Wu(L),Long(Z G),Dai(Z S) Genet Mol Res 0000-00-00

Numerous studies have evaluated the association between the 135G/C polymorphism in the RAD51 gene and risk of acute myel...

XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid L…

Ranganathan(Parvathi),Kashyap(Trinayan),Yu(X… Clin Cancer Res 0000-00-00

...Rad51 and Chk1) mRNA and protein expression and subsequent inhibition of homologous recombination repair and increased s...

Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Fila…

Khade(Nilesh V),Sugiyama(Tomohiko) PLoS One 0000-00-00

...Rad51 (hRAD51) onto ssDNA complexed with yeast RPA in vitro. This is biochemically equivalent to mediator activity becau...

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