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53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.

Li(Minxing),Cole(Francesca),Patel(Dharm S),M… EMBO Rep 0000-00-00

...RAD51 foci form in cells expressing RING-less BRCA1 in response to DNA damage, but the cells nonetheless display the sub...

AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP …

Balaji(Kavitha),Vijayaraghavan(Smruthi),Diao… Mol Cancer Res 0000-00-00

...RAD51 foci formation. As a result, AXL inhibition caused a state of HR-deficiency in the cells, making them sensitive to...

Tyrosine phosphorylation stimulates activity of human RAD51 recombinase through…

Subramanyam(Shyamal),Ismail(Mohammed),Bhatta… Proc Natl Acad Sci U S A 0000-00-00

...RAD51 and properties of the RAD51 nucleoprotein filament. By mimicking RAD51 tyrosine phosphorylation with a nonnatural ...

Characterization of the recombination activities of the Entamoeba histolytica R…

Kelso(Andrew A),Goodson(Steven D),Chavan(Suc… Mol Biochem Parasitol 0000-00-00

...Rad51 recombinase. Here, a biochemical characterization of highly purified ehRad51 protein is presented. The ehRad51 pro...

Pomegranate Intake Protects Against Genomic Instability Induced by Medical X-ra…

Nallanthighal(Sameera),Shirode(Amit B),Judd(… Nutr Cancer 0000-00-00

...Rad51, Rad52 and Brca2) in the liver of PE-treated mice. Likewise, mRNA levels of antioxidant enzymes were reduced (Gpx1...

Cervantes and Quijote protect heterochromatin from aberrant recombination and l…

Ryu(Taehyun),Bonner(Melissa R),Chiolo(Irene) Nucleus 0000-00-00

...Rad51 recruitment. Here we show that HR progression is initially blocked inside the heterochromatin domain by SUMOylatio...

The role of Rad51 in safeguarding mitochondrial activity during the meiotic cel…

Kim(Kyeoung-Hwa),Park(Ji-Hoon),Kim(Eun-Young… Sci Rep 0000-00-00

...Rad51 by injection of Rad51 dsRNA into germinal vesicle-stage oocytes resulted in arrest of meiosis in metaphase I. Rad5...

Ovarian Cancers Harbour Defects in Non-Homologous End Joining Resulting in Resi…

McCormick(Aiste),Donoghue(Peter),Dixon(Miche… Clin Cancer Res 0000-00-00

...RAD51 foci assay.,NHEJ was defective (D) in 4 of 6 cell lines and 20 of 47 primary cultures. NHEJ function was independe...

Boric acid-dependent decrease in regulatory histone H3 acetylation is not mutag…

Pointer(Benjamin R),Schmidt(Martin) FEMS Microbiol Lett 0000-00-00

...Rad51 indicated no elevated level of genotoxic stress during BA exposure. A forward-mutation analysis demonstrated the B...

Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous R…

Han(Deqiang),Liang(Junbo),Lu(Yalan),Xu(Longc… PLoS One 0000-00-00

...RAD51D directly interacted with RNF138. And the recruitment of RAD51D to DNA damage site is delayed and unstable in RNF1...

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