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Kinetochore assembly and heterochromatin formation occur autonomously in Schizo…

Brown(William R A),Thomas(Geraint),Lee(Nicho… Proc Natl Acad Sci U S A 2014-04-03

Kinetochores in multicellular eukaryotes are usually associated with heterochromatin. Whether this heterochromatin simpl...

A CENP-S/X complex assembles at the centromere in S and G2 phases of the human …

Dornblut(Carsten),Quinn(Nadine),Monajambashi… Open Biol 2014-09-12

...CENPs -T, -W, -S and -X. Fluorescence cross-correlation spectroscopy and Förster resonance energy transfer (FRET) reveal...

Mitotic regulator Mis18β interacts with and specifies the centromeric assembly …

Wang(Jianyu),Liu(Xing),Dou(Zhen),Chen(Liang)… J Biol Chem 2014-05-27

The centromere is essential for precise and equal segregation of the parental genome into two daughter cells during mito...

Associations of nailfold capillary abnormalities and immunological markers in e…

Schlager(O),Kiener(H P),Stein(L),Hofkirchner… Scand J Rheumatol 2014-06-11

Nailfold capillaroscopy (NC) and laboratory tests for antinuclear antibodies (ANA) are routinely used in parallel for de...

Molecular characterization and chromosomal distribution of a species-specific t…

Tsoumani(Konstantina T),Drosopoulou(Elena),M… PLoS One 2014-11-24

Satellite repetitive sequences that accumulate in the heterochromatin consist a large fraction of a genome and due to th...

Emerging roles for centromere-associated proteins in DNA repair and genetic rec…

Osman(Fekret),Whitby(Matthew C) Biochem Soc Trans 2014-08-29

Centromere proteins CENP-S and CENP-X are members of the constitutive centromere-associated network, which is a conserve...

Custom cerium oxide nanoparticles protect against a free radical mediated autoi…

Heckman(Karin L),DeCoteau(William),Estevez(A… ACS Nano 2014-08-26

...CeNPs remain monodispersed for long durations in high ionic strength saline. The plasma half-life of the CeNPs is ∼4.0 h...

βTrCP-mediated ubiquitylation regulates protein stability of Mis18β in a cell c…

Kim(Ik Soo),Lee(Minkyoung),Park(Joo Hyeon),J… Biochem Biophys Res Commun 2014-05-06

Ubiquitin E3 ligases including SCF complex are key regulators of cell cycle. Here, we show that Mis18β, a component of M...

Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA doub…

Helfricht(Angela),Wiegant(Wouter W),Thijssen… Cell Cycle 2014-04-21

The cellular response to ionizing radiation (IR)-induced DNA double-strand breaks (DSBs) in native chromatin requires a ...

The centromeric nucleosome-like CENP-T-W-S-X complex induces positive supercoil…

Takeuchi(Kozo),Nishino(Tatsuya),Mayanagi(Kou… Nucleic Acids Res 2014-04-15

The centromere is a specific genomic region upon which the kinetochore is formed to attach to spindle microtubules for f...

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