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Prognostic relevance and therapeutic implications of centromere protein F expre…

Mi(Y-J),Gao(J),Xie(J-D),Cao(J-Y),Cui(S-X),Ga… Dis Esophagus 2014-03-26

Centromere protein F (CENP-F), a cell cycle-regulated centromere protein, has been shown to affect numerous tumorigenic ...

Polo-like kinase 1 licenses CENP-A deposition at centromeres.

McKinley(Kara L),Cheeseman(Iain M) Cell 2014-10-21

To ensure the stable transmission of the genome during vertebrate cell division, the mitotic spindle must attach to a si...

[Detection for therapeutic targets specifically expressed in myeloma side popul…

Tagawa(Hiroyuki) Nihon Rinsho 2014-08-27

ATP binding membrane transporter such as multi drug resistant protein (MDR1) and breast cancer resistance protein (BCRP)...

A cooperative mechanism drives budding yeast kinetochore assembly downstream of…

Hornung(Peter),Troc(Paulina),Malvezzi(France… J Cell Biol 2014-11-18

Kinetochores are megadalton-sized protein complexes that mediate chromosome-microtubule interactions in eukaryotes. How ...

The FACT complex interacts with the E3 ubiquitin ligase Psh1 to prevent ectopic…

Deyter(Gary M R),Biggins(Sue) Genes Dev 2014-10-01

Centromere identity and its epigenetic maintenance require the incorporation of a histone H3 variant called CENP-A at ce...

The centromere: chromatin foundation for the kinetochore machinery.

Fukagawa(Tatsuo),Earnshaw(William C) Dev Cell 2014-11-10

Since discovery of the centromere-specific histone H3 variant CENP-A, centromeres have come to be defined as chromatin s...

Application of mass spectrometry to characterize localization and efficacy of n…

Heckman(Karin L),Erlichman(Joseph),Reed(Ken)… Adv Exp Med Biol 2014-10-01

...CeNPs) in various tissues of healthy mice and in the brains of mice with a model of multiple sclerosis. Thus, ICP-MS ana...

Histone H4 Lys 20 monomethylation of the CENP-A nucleosome is essential for kin…

Hori(Tetsuya),Shang(Wei-Hao),Toyoda(Atsushi)… Dev Cell 2014-08-19

In vertebrate cells, centromeres are specified epigenetically through the deposition of the centromere-specific histone ...

The architecture of CCAN proteins creates a structural integrity to resist spin…

Suzuki(Aussie),Badger(Benjamin L),Wan(Xiaohu… Dev Cell 2014-12-16

Constitutive centromere-associated network (CCAN) proteins, particularly CENP-C, CENP-T, and the CENP-H/-I complex, mech...

Expression and prognostic relevance of centromere protein A in primary osteosar…

Gu(Xiao-Min),Fu(Jie),Feng(Xiao-Jun),Huang(Xu… Pathol Res Pract 2014-10-21

Centromere protein A (CENP-A) is one of the fundamental components of the human active kinetochore and plays important r...

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