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Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irrad…

Quinet(Annabel),Martins(Davi Jardim),Vessoni… Nucleic Acids Res 0000-00-00

...Rev1, is required for postreplicative gap-filling, while Polη and Rev1 are responsible for TLS at stalled replication fo...

Comparative Error-Free and Error-Prone Translesion Synthesis of N(2)-2'-Deoxygu…

Bose(Arindam),Surugihalli(Chaitra),Pande(Par… Chem Res Toxicol 0000-00-00

...Rev1 were simultaneously knocked down. This result strongly suggests that, unlike pol κ, these three TLS polymerases coo...

Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex B…

Yeom(Mina),Kim(In-Hyeok),Kim(Jae-Kwon),Kang(… Chem Res Toxicol 0000-00-00

...REV1, including the N373S variant associated with high risk of cervical cancer, using the recombinant REV1 (residues 330...

Genetic variants and risk of prostate cancer using pathway analysis of a genome…

Kim(Y S),Kim(Y),Choi(J W),Oh(H E),Lee(J H) Neoplasma 0000-00-00

...REV1, DNA directed polymerase (REV1) gene to damaged DNA binding. The third was rs1063134 to potassium channel, inwardly...

Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutag…

Bose(Arindam),Millsap(Amy D),DeLeon(Arnie),R… Chem Res Toxicol 0000-00-00

...Rev1. Up to 75% reduction in TLS occurred when pol η, pol ζ, and Rev1 were simultaneously knocked down, suggesting that ...

Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to sup…

Dai(Chun-Hua),Chen(Ping),Li(Jian),Lan(Tin),C… Oncotarget 0000-00-00

...REV1. Our results indicate that there is a synthetic lethal relationship between pol θ-mediated DNA repair and HR pathwa...

Y-family DNA polymerase-independent gap-filling translesion synthesis across ar…

Hashimoto(Keiji),Bonala(Radha),Johnson(Franc… DNA Repair (Amst) 0000-00-00

...Rev1 gene did not significantly affect TLS. However, knockout of the Rev3l gene, coding for the catalytic subunit of pol...

R.I.P. to the PIP: PCNA-binding motif no longer considered specific: PIP motifs…

Boehm(Elizabeth M),Washington(M Todd) Bioessays 0000-00-00

...Rev1, and MIP motifs, which bind the mismatch repair protein Mlh1. Although these motifs have similar consensus sequence...

Eukaryotic TLS polymerases.

Tomczyk(Przemysław),Synowiec(Ewelina),Wysoki… Postepy Hig Med Dosw (Online) 0000-00-00

...Rev1, κ, η, ι, and polymerase ζ from the B family. There are two mechanisms of TLS polymerases action: polymerase-switch...

Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on T…

Tian(Xu),Patel(Keyur),Ridpath(John R),Chen(Y… PLoS One 0000-00-00

...REV1-deficient DT40 cells at 19.2 μg/L or higher as well as in TK6 cells deficient in polymerase delta subunit 3 (POLD3)...

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