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Expression of amyloid precursor-like protein 2 (APLP2) in glioblastoma is assoc…

Chen(Y),Wang(H),Tan(C),Yan(Y),Shen(J),Huang(… Folia Neuropathol 2018-00-00

...APLP2 expression (p > 0.05). However, when connected to glioblastoma patient's prognosis, a high APLP2 expression was fo...

Comparative binding analysis of WGX50 and Alpha-M with APP family proteins APLP…

Ali(A),Masood(A),Khan(AA),Zhu(FY),Cheema(MAR… Phys Chem Chem Phys 2023-05-31

...APLP2 and -8.25 kcal mol-1 for the WGX-50-APLP2 complex. Our results also elaborate that in the case of their interactio...

APLP2 is predominantly cleaved by β-secretase and γ-secretase in the human brai…

Yanagida(K),Maruyama(R),Tagami(S),Kudo(T),Ok… Psychogeriatrics 2023-03-00

...APLP2. APLP2 is known to play the most important role among them, but the molecular metabolism of APLP2 is only partiall...

Post-translational processing and turnover kinetics of presynaptically targeted…

Lyckman(AW),Confaloni(AM),Thinakaran(G),Siso… J Biol Chem 1998-05-01

...APLP2 was not accompanied by detectable APLP2 fragment peptides, suggesting either that APLP2 either is more rapidly deg...

Combined deletions of amyloid precursor protein and amyloid precursor-like prot…

Needham(BE),Ciccotosto(GD),Cappai(R) Metallomics 2014-03-00

...APLP2) affect metal homeostasis in vitro and in vivo. Analysis of the in vivo effects of the APP and APLP2 knockouts on ...

APLP2 regulates neuronal stem cell differentiation during cortical development.

Shariati(SA),Lau(P),Hassan(BA),Müller(U),Dot… J Cell Sci 2013-03-01

...APLP2 during neurogenesis by silencing APLP2 in vivo in an APP/APLP1 double knockout mouse background. We find that unde...

The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2…

Cappai(R),Cheng(F),Ciccotosto(GD),Needham(BE… J Biol Chem 2005-04-08

...APLP2 inhibit autodegradation, (d) in primary cortical neurons from APP or APLP2 knock-out mice, there is an increased n...

Amyloid precursor-like protein 2 suppresses irradiation-induced apoptosis in Ew…

Peters(HL),Yan(Y),Nordgren(TM),Cutucache(CE)… Cancer Biol Ther 2013-08-00

...APLP2) has recently been implicated in the survival of cancer cells and in our current study, APLP2's contribution to th...

Amyloid precursor-like protein 2 interacts with claudin-7 and affects ovarian c…

Dahiya(N) Future Sci OA 2020-03-16

...APLP2) was found directly associated with CLDN7 in ovarian cancer cell line OVCA420. In addition, APLP2 showed increased...

APP, APLP2 and LRP1 interact with PCSK9 but are not required for PCSK9-mediated…

Fu(T),Guan(Y),Xu(J),Wang(Y) Biochim Biophys Acta Mol Cell… 2017-09-00

...Aplp2-/-, Aplp2-depleted App-/-, or liver-specific Lrp1-/- mice resulted in similar reductions in the levels of hepatic ...

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