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Dbp7 interacts with RNA exosome component Dis3 to mediate CENP-A loading to c...

Gao(J),Gao(F),Dong(Q),Li(Z),Mao(L),Ali(M),... Genome Biol 2026-06-02

Centromeres are crucial for proper chromosome segregation during cell division. Centromeres in most eukaryotes are epige...

SPINDOC functions as a mitotic molecular counter to coordinate spatiotemporal...

Zhang(Z),Zhang(X),Liu(Y),Wang(K),Chen(Z),Z... Cell Rep 2026-07-28

Cell cycle-dependent maintenance of centromere protein A (CENP-A) levels and its spatiotemporal assembly are essential f...

Application of cerium dioxide nanoparticles in the treatment of intervertebra...

Cao(R),Wang(P),Guo(S),Yang(Z),Li(D),Pan(X)... J Transl Med 2026-06-23

Oxidative stress (OS) induced by local reactive oxygen species (ROS) accumulation plays a vital role in initiating and a...

CeO2-Loaded Shear-Thinning Hydrogel Combined with Dental Pulp Stem Cells Modu...

Sun(X),Yan(J),Guo(F),Sun(H),Xie(X),Su(N),S... ACS Appl Mater Interfaces 2026-07-08

Stem cell transplantation holds great promise for facial nerve repair, yet its efficacy is largely constrained by the ex...

Structural basis of βKNL2 centromeric targeting mechanism and its role in pla...

Yadala(R),Camara(AS),Yalagapati(SP),Vaculí... Nucleic Acids Res 2026-06-22

The kinetochore is an essential protein complex that ensures proper chromosome segregation during cell division. Kinetoc...

Structural dynamics in the CENP-A nucleosome impacted by protein-protein inte...

Ghosh Moulick(A),Erhardt(S),Wenzel(W),Kozl... Nanoscale 2026-07-23

Noncanonical nucleosomes at the centromere contain the histone variant CENP-A, which plays a crucial role in chromosome ...

Architecture and function of holocentric CENP-A-independent inner kinetochore...

Yu(C),Sankaranarayanan(SR),Cornilleau(G),H... Sci Adv 2026-06-19

Kinetochores are essential macromolecular complexes anchoring chromosomes to the mitotic spindle, ensuring faithful cell...

Scm3 interacts with the N-terminal tail of Cse4 to regulate kinetochore assem...

Agarwal(P),Alekar(A),Mallick(S),Shah(J),Mi... Genetics 2026-07-06

The kinetochore is a multiprotein complex formed at the centromeres and is essential for the faithful chromosome segrega...

Determinants of centromeric nucleosome conformation.

Paintsil(EA),Lee(J),Zahorodny(SSM),Wereszc... bioRxiv 2026-05-17

Centromeric chromatin is defined by the presence of the histone H3 variant CENP-A, which forms a specialized nucleosome ...

Meiotic CENP-C supports centromere assembly and kinetochore recruitment in sp...

Keegan(RS),Malkeyeva(D),Weever(MB),Dunleav... J Cell Biol 2026-09-07

The centromere is the chromosomal site of kinetochore assembly, defined by the histone H3 variant CENP-A. In each cell c...

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