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Cloning, characterization and analysis of the 5' regulatory region of zebrafish…

Silva(I A L),Conceição(N) Comp Biochem Physiol B Bioche… 2016-01-26

...ERCC2 encodes an ATP-dependent 5'-3' helicase of 760 amino acids. There are few transcription factors known to be involv...

An association of selected ERCC2 and ERCC5 genes polymorphisms, the level of ox…

Kabzinski(Jacek),Przybylowska(Karolina),Dzik… Cancer Biomark 2016-06-27

...ERCC2 gene and allele Asp of 312Asn/Asp polymorphism of ERCC2 gene may be associated with an increased risk of colorecta...

New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts.

Kunze(Sarah),Dalke(Claudia),Fuchs(Helmut),Kl… PLoS One 2016-02-25

...Ercc2 gene leading to a Ser737Pro exchange. During embryonic development, the mutant eyes did not show major changes. Po...

Genetic variability of genes involved in DNA repair influence treatment outcome…

Wang(M J),Zhu(Y),Guo(X J),Tian(Z Z) Genet Mol Res 2016-06-06

We conducted a perspective study to investigate the role of ERCC1 (rs11615), ERCC2 (rs13181 and rs1799793), ERCC4 (rs180...

Investigation of ERCC1 and ERCC2 gene polymorphisms and response to chemotherap…

Zhang(Q),Lv(L Y),Li(B J),Zhang(J),Wei(F) Genet Mol Res 2016-07-11

We assessed the role of single nucleotide polymorphisms (SNPs) in ERCC1 and ERCC2 genes in the clinical outcomes for ost...

Technical reproducibility of single-nucleotide and size-based DNA biomarker ass…

Zhang(Shenli),Tan(Iain B),Sapari(Nur S),Grab… J Mol Diagn 2016-01-14

...ERCC2 (rs13181) in 56 FFPE DNA samples. By using PCR, followed by size-based gel electrophoresis, we also examined TYMS ...

ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with…

Groenendijk(Floris H),de Jong(Jeroen),Franse… Eur Urol 2016-11-14

...ERCC2 missense mutations, recently found associated with response to NAC, were more common in complete responders; howev...

Association of chromosome 19 to lung cancer genotypes and phenotypes.

Wang(Xiangdong),Zhang(Yong),Nilsson(Carol L)… Cancer Metastasis Rev 2016-10-31

...ERCC2, XRCC1), TGFβ1 pathway activation genes (TGFB1, LTBP4), Dyrk1B, and potential oncogenesis protector genes such as ...

Association between ERCC1 and ERCC2 gene polymorphisms and chemotherapy respons…

Cao(Z H),Yin(H P),Jiang(N),Yu(B) Genet Mol Res 2016-06-06

We aimed to evaluate the influence of four SNPs in ERCC1 and ERCC2 on the response to cisplatin-based treatment and on c...

Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in…

Boccard(Sandra G),Marand(Sandie V),Geraci(Sa… Oncotarget 2016-08-11

...ercc2, mutyh, and pnkp significantly sensitized cells to chemotherapy, increasing cell death by up to 25%. In vivo we ob...

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