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Novel Insights into the Enigmatic Genetics of Male Breast Cancer in China.

Lang(GT),Weng(XL),Liu(Y),Hu(X),Shao(ZM),Hu(Z) Pathophysiology 2026-01-20

...RAD50, DMD, ARSA, and ABCC6 demonstrating recurrent mutations in MaBC. As the inaugural germline genomic investigation o...

[Rosai-Dorfman disease of the breast: a clinicopathological and molecular genet…

Huang(ZD),Zhai(BY),Xu(C),Ding(Y),Zhang(ZH),W… Zhonghua Bing Li Xue Za Zhi 2026-03-08

...RAD50, MRE11, and BRIP1-in three cases. One case showed somatic mutations in genes associated with signaling pathways an...

Novel RAD50 variants lead to Nijmegen Breakage Syndrome-like disorder and unpla…

Gong(Y),Jiang(M),Wu(S),Guo(S),Lyu(Y) Front Endocrinol (Lausanne) None

...RAD50 gene. Western blotting revealed the presence of the Flag-tag and EGFP in RAD50-wt, but not in RAD50-mut (p.His1269...

YEATS2 promotes DNA repair and induces anoikis resistance by enhancing chromati…

Li(H),Song(Y),Cong(Y),Wang(C),Chen(K),Liu(C)… Oncogene 2026-03-00

...RAD50. Mechanistically, YEATS2 increases chromatin accessibility at the RAD50 promoter region by recognizing H3K27ac and...

Potential advantage of clinical exome sequencing in BRCA1/2-negative families: …

Dell'Elice(A),Palmarini(C),Anaclerio(F),Pile… J Med Genet 2026-07-24

...RAD50, BLM, WRN, PMS1 and FANCA. These variants may represent candidate susceptibility loci requiring further clinical a...

Multifaceted roles of PDS5B in RAD51-dependent homology-directed DNA repair and…

Katz(JN),Samentar(L),Fang(Q),Ji(JH),Li(W),Ga… Nat Commun 2026-05-20

...RAD50-NBS1. DNA binding activity resides within the disordered C-terminal region of PDS5B, and testing of a DNA binding ...

Rap1-mediated steric hindrance protects telomeres from MRX sensing.

Mattarocci(S),Reginato(G),Cannavo(E),Roisné-… Nat Struct Mol Biol 2026-06-00

...Rad50-Xrs2NBS1 (MRXMRN) complex. The response to telomere length is thought to correlate with the number of DNA-bound te...

The 1H, 15N and 13C backbone resonance assignments of an intrinsically disorder…

Dinh(HH),Jasper(AM),Baudin(A),Sung(P),Libich… Biomol NMR Assign 2026-09-04

...RAD50, RAD51, MYC, and RB. Here, we report the backbone resonance assignments of a BRCA1 IDR construct spanning residues...

Functional analysis of novel and recurrent RINT1 variants in patients with infa…

Aoki(T),Inui(A),Ogata(Y),Igarashi(A),Yanagi(… J Hum Genet 2026-01-00

Rad50-interacting protein (RINT1) interacts with the endoplasmic reticulum (ER) tethering and SNARE complex, playing a c...

Macrophage-derived exosomes carrying RAD50 attenuate oxidative DNA damage and p…

Meng(J),Zhang(Z),Li(N),Li(Q),Tian(J),Song(D)… Nanomedicine (Lond) 2026-09-20

...RAD50 was detected among 3603 exosomal proteins and ranked in the top tier of the displayed abundance panel, and exosome...

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