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Integrated analysis of whole-exome sequencing and transcriptome profiling in ...

Codina-Solà(Marta),Rodríguez-Santiago(Benj... Mol Autism 2015-05-13

...RIT1, ALG9). The analysis of rare inherited variants showed enrichment in relevant pathways such as the PI3K-Akt signali...

Oncogenic RIT1 mutations in lung adenocarcinoma.

Berger(A H),Imielinski(M),Duke(F),Wala(J),... Oncogene 2015-04-14

...RIT1 in ∼2% of lung adenocarcinoma cases that cluster in a hotspot near the switch II domain of the protein. RIT1 switch...

Comprehensive molecular profiling of lung adenocarcinoma.

Nature 2014-09-16

...RIT1 activating mutations and newly described loss-of-function MGA mutations which are mutually exclusive with focal MYC...

Next-generation sequencing identifies rare variants associated with Noonan sy...

Chen(Peng-Chieh),Yin(Jiani),Yu(Hui-Wen),Yu... Proc Natl Acad Sci U S A 2014-10-03

...RIT1) and mitogen-activated protein kinase kinase 1 (MAP2K1) and previously unseen loss-of-function variants in RAS p21 ...

Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway ...

Aoki(Yoko),Niihori(Tetsuya),Banjo(Toshihir... Am J Hum Genet 2013-09-16

...RIT1, encoding a member of the RAS subfamily, in 17 of 180 individuals (9%) with Noonan syndrome or a related condition ...

Natural variation for Fe-efficiency is associated with upregulation of Strate...

Kabir(Ahmad H),Paltridge(Nicholas G),Able(... Planta 2012-09-24

...RIT1 were upregulated in Fe-deficient roots of Santi. Expression of HA1 (proton extrusion) was also significantly higher...

cDNA cloning, sequence identification and tissue expression distribution of t...

Liu(G Y) Mol Biol Rep 2009-05-12

...RIT1 gene encodes a protein of 219 amino acids and has high homology with the GTP-binding protein Rit1 (RIT1) of two spe...

Immune transcriptome alterations in the temporal cortex of subjects with autism.

Garbett(Krassimira),Ebert(Philip J),Mitche... Neurobiol Dis 2008-11-07

...RIT1, SFN, GADD45B, HSPA6, HSPB8 and SERPINH1). Overall, these expression patterns appear to be more associated with the...

Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication s...

Kamimura(K),Mishima(Y),Obata(M),Endo(T),Ao... Oncogene 2007-10-11

...Rit1 is involved in T-cell development and undergoes chromosomal rearrangements in human T-cell leukemias. Thymocytes of...

Radiation carcinogenesis in mouse thymic lymphomas.

Kominami(Ryo),Niwa(Ohtsura) Cancer Sci 2006-08-16

...Rit1 tumor suppressor gene and the other is Mtf-1 gene affecting tumor susceptibility.

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