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A network of players in H3 histone variant deposition and maintenance at centro…

Müller(Sebastian),Almouzni(Geneviève) Biochim Biophys Acta 2014-04-18

Centromeres are key chromosomal landmarks important for chromosome segregation and are characterized by distinct chromat...

Rapidly cleaving bovine two-cell embryos have better developmental potential an…

Orozco-Lucero(Ernesto),Dufort(Isabelle),Robe… Mol Reprod Dev 2014-09-15

Mammalian embryos that rapidly reach the two-cell stage in culture have a higher probability of becoming viable blastocy...

The architecture of CCAN proteins creates a structural integrity to resist spin…

Suzuki(Aussie),Badger(Benjamin L),Wan(Xiaohu… Dev Cell 2014-12-16

Constitutive centromere-associated network (CCAN) proteins, particularly CENP-C, CENP-T, and the CENP-H/-I complex, mech...

Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore…

Bergmann(Jan H),Jakubsche(Julia N),Martins(N… J Cell Sci 2013-04-04

Human kinetochores are transcriptionally active, producing very low levels of transcripts of the underlying alpha-satell...

Anti-centromere antibodies in a large cohort of systemic sclerosis patients: co…

Mahler(Michael),You(Daniel),Baron(Murray),Ta… Clin Chim Acta 2013-07-08

Anti-centromere antibodies (ACA) are useful biomarkers in the diagnosis of systemic sclerosis (SSc) where they are found...

Clinical correlates of CENP-A and CENP-B antibodies in a large cohort of patien…

Hudson(Marie),Mahler(Michael),Pope(Janet),Yo… J Rheumatol 2013-01-22

To study the clinical phenotypes of centromeric proteins (CENP)-A- and CENP-B-positive patients with systemic sclerosis ...

Arabidopsis thaliana AUCSIA-1 regulates auxin biology and physically interacts …

Molesini(Barbara),Pandolfini(Tiziana),Pii(Yo… PLoS One 2013-02-22

Aucsia is a green plant gene family encoding 44-54 amino acids long miniproteins. The sequenced genomes of most land pla...

Kinetochores accelerate centrosome separation to ensure faithful chromosome seg…

McHedlishvili(Nunu),Wieser(Samuel),Holtacker… J Cell Sci 2013-04-03

At the onset of mitosis, cells need to break down their nuclear envelope, form a bipolar spindle and attach the chromoso...

Computational screening and molecular dynamics simulation of disease associated…

Kumar(Ambuj),Purohit(Rituraj) Mutat Res 2013-02-26

Aneuploidy and chromosomal instability (CIN) are hallmarks of most solid tumors. Mutations in centroemere proteins have ...

Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells t…

Mayes(Patrick A),Degenhardt(Yan Y),Wood(Andr… Int J Cancer 2013-01-29

Inhibition of centromere-associated protein-E (CENP-E) has demonstrated preclinical anti-tumor activity in a number of t...

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