Centromeres are key chromosomal landmarks important for chromosome segregation and are characterized by distinct chromat...
Mammalian embryos that rapidly reach the two-cell stage in culture have a higher probability of becoming viable blastocy...
Constitutive centromere-associated network (CCAN) proteins, particularly CENP-C, CENP-T, and the CENP-H/-I complex, mech...
Human kinetochores are transcriptionally active, producing very low levels of transcripts of the underlying alpha-satell...
Anti-centromere antibodies (ACA) are useful biomarkers in the diagnosis of systemic sclerosis (SSc) where they are found...
To study the clinical phenotypes of centromeric proteins (CENP)-A- and CENP-B-positive patients with systemic sclerosis ...
Aucsia is a green plant gene family encoding 44-54 amino acids long miniproteins. The sequenced genomes of most land pla...
At the onset of mitosis, cells need to break down their nuclear envelope, form a bipolar spindle and attach the chromoso...
Aneuploidy and chromosomal instability (CIN) are hallmarks of most solid tumors. Mutations in centroemere proteins have ...
Inhibition of centromere-associated protein-E (CENP-E) has demonstrated preclinical anti-tumor activity in a number of t...
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