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Tightly-bound to DNA proteins in rat experimental hepatomas and normal liver ce…

Labeikytė(D),Borutinskaitė(V),Legzdiņš(N),Sj… Exp Oncol 2012-02-21

...RAD50, coiled-coil domain-containing protein 41, structural maintenance of chromosomes protein1A and some ATP -dependent...

PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusi…

Reynolds(Gloria E),Gao(Qing),Miller(Douglas)… DNA Repair (Amst) 2012-02-27

...Rad50/Xrs2 complex that is required for chromosome healing due to its role in the processing of DSBs and recruitment of ...

LINE-1 retrotransposition in human neuroblastoma cells is affected by oxidative…

Giorgi(Gianfranco),Marcantonio(Pamela),Del R… Cell Tissue Res 2012-07-16

...RAD50, NBN and ERCC1 (all involved in DNA repair) have also been found. Thus, oxidative stress can cause L1 dysregulatio...

Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presen…

Sun(Jingxin),Lee(Kyung-Jong),Davis(Anthony J… J Biol Chem 2012-04-16

...Rad50/Xrs2 (MRX) complex. To study the interrelationship between human Ku and Mre11 or Mre11/Rad50 (MR), we established ...

Structural and functional insights into DNA-end processing by the archaeal HerA…

Blackwood(John K),Rzechorzek(Neil J),Abrams(… Nucleic Acids Res 2012-06-15

...Rad50 proteins during HR-dependent DNA repair. Here we show that HerA and NurA must interact in a complex with specific ...

Regulatory networks integrating cell cycle control with DNA damage checkpoints …

Langerak(Petra),Russell(Paul) Philos Trans R Soc Lond B Bio… 2012-03-01

...Rad50-Nbs1 protein complex and Ctp1/Sae2/CtIP, and the checkpoint kinases Tel1/ATM and Rad3/ATR. Here, we review recent ...

Mitoxantrone in combination with a DNA-PK inhibitor: possible therapy of promye…

Mikusová(V),Tichý(A),Rezáčová(M),Vávrová(J) Folia Biol (Praha) 2012-06-05

...Rad50 and Nbs1, which are important in both types of the repair processes (NHEJ as well as homologou...

Hepatoprotective effects and mechanisms of dehydrocavidine in rats with carbon …

Wang(Tao),Zhao(Li-Jun),Li(Ping),Jiang(Hua),L… J Ethnopharmacol 2012-05-03

...Rad50).,DC treatment significantly inhibited the loss of body weight and the increase of liver weight induced by CCl4. D...

Occult hepatitis C virus elicits mitochondrial oxidative stress in lymphocytes …

Bhargava(Arpit),Raghuram(Gorantla V),Pathak(… Free Radic Biol Med 2012-03-27

...Rad50, and Nbs1) and altered mitochondrial DNA content. Increased mitochondrial membrane depolarization and circulating ...

Variants in activators and downstream targets of ATM, radiation exposure, and c…

Brooks(Jennifer D),Teraoka(Sharon N),Reiner(… Hum Mutat 2012-04-23

...RAD50, TP53BP1) involved in the DNA DSBs response were genotyped. No variants or haplotypes were associated with CBC ris...

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