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A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora…

De Antoni(Anna),Maffini(Stefano),Knapp(Stefa… J Cell Biol 2013-01-08

By phosphorylating Thr3 of histone H3, Haspin promotes centromeric recruitment of the chromosome passenger complex (CPC)...

Human Asunder promotes dynein recruitment and centrosomal tethering to the nucl…

Jodoin(Jeanne N),Shboul(Mohammad),Sitaram(Po… Mol Biol Cell 2013-06-03

Recruitment of dynein motors to the nuclear surface is an essential step for nucleus-centrosome coupling in prophase. In...

Epigenetic regulation of condensin-mediated genome organization during the cell…

Tanaka(Atsunari),Tanizawa(Hideki),Sriswasdi(… Mol Cell 2013-02-21

Complex genome organizations participate in various nuclear processes including transcription, DNA replication, and repa...

Sim3 shares some common roles with the histone chaperone Asf1 in fission yeast.

Tanae(Katsuhiro),Horiuchi(Tomitaka),Yamakawa… FEBS Lett 2013-01-25

An H3/H4 histone chaperone, Asf1, plays an essential role in maintaining genomic stability in many species, including fi...

Low prevalence of autoantibodies to CENP-H, -I, -K, -L, -M, -N, -T and -U in a …

Saito(Akiko),Muro(Yoshinao),Sugiura(Kazumits… Immunopharmacol Immunotoxicol 2013-07-09

...CENPs, no sera reacted to any other 7 CENPs, except 1 serum, which reacted weakly to CENP-T. We were unable to find any ...

Transcription in the maintenance of centromere chromatin identity.

Chan(F Lyn),Wong(Lee H) Nucleic Acids Res 2013-02-22

Recent evidence has shown that transcription is permissible through the purportedly repressive centromere domain, and th...

Combined evaluation of centromere protein H and Ki-67 as prognostic biomarker f…

He(W L),Li(Y H),Yang(D J),Song(W),Chen(X L),… Eur J Surg Oncol 2013-03-01

Centromere protein H (CENP-H) is one of the essential components of the human active kinetochore which close links with ...

Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dy…

Wang(Xiwei),Zhuang(Xiaoxuan),Cao(Dan),Chu(Yo… J Biol Chem 2013-02-19

Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microt...

A cell-free system for functional centromere and kinetochore assembly.

Guse(Annika),Fuller(Colin J),Straight(Aaron … Nat Protoc 2013-01-28

This protocol describes a cell-free system for studying vertebrate centromere and kinetochore formation. We reconstitute...

Spatiotemporal dynamics of Spc105 regulates the assembly of the Drosophila kine…

Venkei(Zsolt),Przewloka(Marcin R),Ladak(Yase… Open Biol 2013-06-27

The formation of kinetochores shortly before each cell division is a prerequisite for proper chromosome segregation. The...

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