Literature Search

Chen(Xuefeng),Niu(Hengyao),Chung(Woo-Hyun),Z… Nat Struct Mol Biol 2011-11-08

...Rad50-Xrs2 complex with Sae2 initiates resection, whereas two nucleases, Exo1 and Dna2, and the DNA helicase-topoisomera...

Rebbeck(Timothy R),Mitra(Nandita),Domchek(Su… Cancer Res 2011-10-25

...RAD50, RAD51, RAP80, and TOPBP1, and was associated with time to breast and ovarian cancer diagnosis. Statistically sign...

Herdendorf(Timothy J),Nelson(Scott W) Biochemistry 2011-09-09

...Rad50 (MR complex), which are a nuclease and ATPase, respectively, is involved in the initial processing of DSBs. Rad50 ...

Darzynkiewicz(Zbigniew),Traganos(Frank),Zhao… Methods Cell Biol 2011-11-07

...Rad50 homolog, and Nijmegen Breakage Syndrome 1 (NMR1) into DNA damage sites was assessed by laser scanning cytometry as...

Zheng(Jian),Zhang(Chun),Jiang(Lan),You(Yongh… Mol Carcinog 2011-09-21

...RAD50/NBS1) complex, NBS1 plays an important role in cellular response to DNA damage and the maintenance of chromosomal ...

Garner(Kristen M),Eastman(Alan) BMC Cancer 2011-09-16

The Mre11/Rad50/Nbs1 (MRN) complex is a regulator of cell cycle checkpoints and DNA repair. Defects in MRN can lead to d...

Ruiz-Gómez(Miguel J) Indian J Exp Biol 2011-06-21

...Rad50 in telomere stabilization. Inactivation of any of these genes lead to a shortening of telomeres, while in ku70 tel...

Baydoun(Hicham H),Pancewicz(Joanna),Nicot(Ch… Blood 2011-09-08

...RAD50/NBS1 complex and favors the error-prone nonhomologous-end-joining (NHEJ) DNA-repair pathway instead. As a result, ...

Sundararajan(Rangapriya),Freudenreich(Cather… PLoS Genet 2011-07-21

...Rad50-Xrs2), a central component of DSB repair which is required to repair breaks at CAG repeats, failed to elicit repea...

De la Rosa(Metzere Bierlein),Nelson(Scott W) J Biol Chem 2011-09-16

...Rad50 (gp46). Mutation of either the D-loop aspartate or the Walker A asparagine results in dramatic reductions in ATP a...