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Error-prone translesion replication of damaged DNA suppresses skin carcinogenes…

Tsaalbi-Shtylik(A),Verspuy(JW),Jansen(JG),Re… Proc Natl Acad Sci U S A 2009-12-22

...Rev1. Despite a defect in UV-induced mutagenesis, skin carcinogenesis was accelerated in these mice. This paradoxical ph...

Interactions in the error-prone postreplication repair proteins hREV1, hREV3, a…

Murakumo(Y),Ogura(Y),Ishii(H),Numata(S),Ichi… J Biol Chem 2001-09-21

...Rev1 and DNA polymerase zeta that consists of scRev3 and scRev7 proteins. Recently, the human REV1 (hREV1) and REV3 (hRE...

Regulation of translesion DNA synthesis: Posttranslational modification of lysi…

McIntyre(Justyna),Woodgate(Roger) DNA Repair (Amst) 2016-02-08

...Rev1 and we will discuss the potential regulatory effects of such modification in controlling TLS in vivo.

DNA repair in antibody somatic hypermutation.

Casali(P),Pal(Z),Xu(Z),Zan(H) Trends Immunol 2006-07-00

...Rev1, pol zeta and, perhaps, pol iota, which are error-prone and crucially insert mismatches or mutations while repairin...

Separate roles of structured and unstructured regions of Y-family DNA polymeras…

Ohmori(H),Hanafusa(T),Ohashi(E),Vaziri(C) Adv Protein Chem Struct Biol 2009-00-00

...Rev1 (all classified as "Y-family" members) and Pol zeta (a "B-family" member). Y-family DNA polymerases have highly str...

SARS-CoV-2 hijacks host cell genome instability pathways.

Victor(J),Jordan(T),Lamkin(E),Ikeh(K),March(… Res Sq 2022-04-14

...REV1-targeting translesion DNA synthesis inhibitor, JH-RE-06, suppresses SARS-CoV-2 proliferation and dramatically repre...

Cell-free Xenopus egg extracts for studying DNA damage response pathways.

Cupello(Steven),Richardson(Christine),Yan(Sh… Int J Dev Biol 0000-00-00

...REV1) in the DDR pathways. A better understanding of DDR pathways using Xenopus egg extracts has opened new avenues for ...

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability d…

Gupta(SV),Campos(L),Schmidt(KH) Genetics 2023-00-04

...Rev1/Pol ζ mutasome suggests that under oxidative stress successful DNA synthesis during DNA break repair depends on tra...

Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requi…

Schürer(KA),Rudolph(C),Ulrich(HD),Kramer(W) Genetics 2004-04-00

...REV1 and the synergy with mutations in base and nucleotide excision repair suggest an involvement of MPH1 in error-free ...

DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibit…

Diamant(N),Hendel(A),Vered(I),Carell(T),Reis… Nucleic Acids Res 2012-01-00

...Rev1. Analysis of TLS using a high-resolution gapped-plasmid assay system in cell populations enriched by centrifugal el...

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