Literature Search

Bilbao(Cristina),Ramírez(Raquel),Rodríguez(G… Eur J Cancer 2011-01-19

...RAD50 (n=7, 17%), MRE11, ATR and BRCA1 (n=6, 15%), and by CtIP and MCPH1 (n=5, 12%). While DSB biallelic mutations were ...

Orazio(Nicole I),Naeger(Colleen M),Karlseder… J Virol 2011-03-07

...Rad50-Nbs1 (MRN) complex. Since members of the RecQ helicase family function together with MRN in genome maintenance, we...

Chen(Xi),Tomkinson(Alan E) J Biol Chem 2011-03-24

...Rad50-Xrs2, Dnl4-Lif1, and Nej1. Here, we examined the role of Nej1 in NHEJ by a combination of molecular genetic and bi...

Kozlov(Sergei V),Graham(Mark E),Jakob(Burkha… J Biol Chem 2011-05-16

...Rad50-Nbs1 complex, where it is fully activated. In human cells, the activation process involves autophosphorylation on ...

Guo(Zhi),Deshpande(Rajashree),Paull(Tanya T) Cell Cycle 2011-05-02

...Rad50-Nbs1 (MRN) complex. ATM can also be activated by oxidative stress directly in the form of exposure to H2O2. The ac...

Jiang(Lan),Liang(Jianying),Jiang(Mingjun),Yu… Eur J Haematol 2011-03-31

...RAD50 and NBS1), NBS1 plays an important role in cellular response to DNA damage and the maintenance of chromosomal inte...

Eid(Wassim),Steger(Martin),El-Shemerly(Mahmo… EMBO Rep 2011-03-02

...RAD50-NBS1 (MRN) and CtIP, followed by a processive step involving helicases and exonucleases such as exonuclease 1 (EXO...

Capraro(Valérie),Zane(Linda),Poncet(Delphine… Exp Hematol 2011-03-10

...RAD50 are independent prognostic factors for survival.,Each leukemia subtype possesses specific telomere dysregulations ...

Kuroda(Shinji),Fujiwara(Toshiya),Shirakawa(Y… Cancer Res 2011-02-07

...Rad50, and NBS1, which senses DSBs. Subsequently, the phosphorylation of cellular ataxia-telangiectasia mutated protein ...

Limbo(Oliver),Porter-Goff(Mary E),Rhind(Nich… Mol Cell Biol 2011-02-24

...Rad50-Nbs1(Xrs2) (MRN) nucleolytic protein complex in association with the Tel1(ATM) checkpoint kinase and the Ctp1(CtIP...