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Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dy…

Wang(Xiwei),Zhuang(Xiaoxuan),Cao(Dan),Chu(Yo… J Biol Chem 2013-02-19

Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microt...

Anaphase-promoting complex/cyclosome-mediated proteolysis of Ams2 in the G1 pha…

Trickey(Michelle),Fujimitsu(Kazuyuki),Yamano… J Biol Chem 2013-03-26

Histone transcription and deposition are tightly regulated with the DNA replication cycle to maintain genetic integrity....

Acidic nucleoplasmic DNA-binding protein (And-1) controls chromosome congressio…

Jaramillo-Lambert(Aimee),Hao(Jing),Xiao(Haij… J Biol Chem 2013-03-26

The centromere is an epigenetically designated chromatin domain that is essential for the accurate segregation of chromo...

Weighted gene co-expression network analysis in identification of endometrial c…

Zhu(Xiao-Lu),Ai(Zhi-Hong),Wang(Juan),Xu(Yan-… Asian Pac J Cancer Prev 2013-06-10

Endometrial cancer (EC) is the most common gynecologic malignancy. Identification of potential biomarkers of EC would be...

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition oc…

Lando(David),Endesfelder(Ulrike),Berger(Hara… Open Biol 2013-06-19

The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by ...

Factors that promote H3 chromatin integrity during transcription prevent promis…

Choi(Eun Shik),Strålfors(Annelie),Catania(Sa… PLoS Genet 2013-01-04

Specialized chromatin containing CENP-A nucleosomes instead of H3 nucleosomes is found at all centromeres. However, the ...

Centromere architecture breakdown induced by the viral E3 ubiquitin ligase ICP0…

Gross(Sylvain),Catez(Frédéric),Masumoto(Hiro… PLoS One 2013-03-19

...CENPs), namely CENP-A, the centromeric histone H3 variant, CENP-B and CENP-C. Following ICP0-induced centromere modifica...

Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U…

Eskat(Anja),Deng(Wen),Hofmeister(Antje),Rudo… PLoS One 2013-03-06

Kinetochores are multi-protein megadalton assemblies that are required for attachment of microtubules to centromeres and...

Combined evaluation of centromere protein H and Ki-67 as prognostic biomarker f…

He(W L),Li(Y H),Yang(D J),Song(W),Chen(X L),… Eur J Surg Oncol 2013-03-01

Centromere protein H (CENP-H) is one of the essential components of the human active kinetochore which close links with ...

A cell-free system for functional centromere and kinetochore assembly.

Guse(Annika),Fuller(Colin J),Straight(Aaron … Nat Protoc 2013-01-28

This protocol describes a cell-free system for studying vertebrate centromere and kinetochore formation. We reconstitute...

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