Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microt...
Histone transcription and deposition are tightly regulated with the DNA replication cycle to maintain genetic integrity....
The centromere is an epigenetically designated chromatin domain that is essential for the accurate segregation of chromo...
Endometrial cancer (EC) is the most common gynecologic malignancy. Identification of potential biomarkers of EC would be...
The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by ...
Specialized chromatin containing CENP-A nucleosomes instead of H3 nucleosomes is found at all centromeres. However, the ...
...CENPs), namely CENP-A, the centromeric histone H3 variant, CENP-B and CENP-C. Following ICP0-induced centromere modifica...
Kinetochores are multi-protein megadalton assemblies that are required for attachment of microtubules to centromeres and...
Centromere protein H (CENP-H) is one of the essential components of the human active kinetochore which close links with ...
This protocol describes a cell-free system for studying vertebrate centromere and kinetochore formation. We reconstitute...
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