...RAD50-NBS1 (MRN) complex that activates ataxia telangiectasia mutated (ATM) kinase and early checkpoint response. Ectopi...
...Rad50-Nbs1 (MRN) complex is the first sensor of double-strand breaks, its role in double-strand break (DSB) signaling is...
...Rad50, were detected. These data show, for the first time, that the induction of apoptosis by docetaxel requires DNA rep...
...RAD50/NBS1 protein complex, however deficiency of either protein does not result in the same clinical features. Mutation...
...Rad50-Xrs2 complex and Sae2, while the second step employs the exonuclease Exo1 and/or the helicase-topoisomerase comple...
...RAD50, BRIP1 and PALB2 have been described to be high or moderate penetrance breast cancer susceptibility genes, all con...
...rad50, mre11, herA, nurA, and xpg/fen1 genes. Phenotypic analyses of the gene-disrupted strains showed that the xpb and ...
...RAD50 and Nijmegen breakage syndrome 1 (NBS1; also known as nibrin) proteins is central to the DDR, and recent insights ...
...RAD50/NBS1 (MRN) complex, which plays a major role in the early phase of the complex cellular response to double strand ...
...RAD50, and NBS1 (MRN); and Replication protein A (RPA). Resection occurs via two routes. In one, BLM and DNA2 physically...
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