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Development of a Plant-Expressed Subunit Vaccine against Brucellosis.

Rutkowska(DA),Du Plessis(LH),Suleman(E),O'Ke… Microorganisms 2024-05-22

...Rev1 vaccine. Here, we have successfully shown the assembly, safety and protective efficacy of plant-expressed chimeric ...

Generation, repair and replication of guanine oxidation products.

Kino(K),Hirao-Suzuki(M),Morikawa(M),Sakaga(A… Genes Environ 2017-00-00

...REV1. (ii) Several enzymes exhibit incision activity towards Oz. (iii) Since the redox potential of GG is lower than tha...

DNA polymerase zeta can efficiently replicate structures formed by AT/TA repeat…

Das(M),Hile(SE),Brewster(J),Boer(JL),Bezalel… Nucleic Acids Res 2025-01-24

...Rev1 protein and the modifiable lysine 164 of proliferating cell nuclear antigen to prevent deletions at AT/TA repeats s...

The levels of p53 govern the hierarchy of DNA damage tolerance pathway usage.

Castaño(BA),Schorer(S),Guo(Y),Calzetta(NL),G… Nucleic Acids Res 2024-04-24

...REV1, PCNA, PRIMPOL, HLTF and ZRANB3 to the DNA replication rate. Our results suggest that the levels of p53 are central...

Translesion polymerases and DNA-protein crosslink repair shapes the cellular re…

Blouin(T),Ampolini(E),Stayer(K),Suresh(P),Mi… Nucleic Acids Res 2025-09-05

...Rev1 and Pol η function together to prevent FA mutagenesis. Overall, these results outline the mechanisms by which TLS a...

WRN and WRNIP1 ATPases impose high fidelity on translesion synthesis by Y-famil…

Yoon(JH),Sellamuthu(K),Prakash(L),Prakash(S) Elife 2025-09-03

...Rev1 in TLS. Among these proteins, WRN possesses a 3'→5' exonuclease activity and an ATPase/3'→5' DNA helicase activity,...

Postreplication gaps at UV lesions are signals for checkpoint activation.

Callegari(AJ),Clark(E),Pneuman(A),Kelly(TJ) Proc Natl Acad Sci U S A 2010-05-04

...Rev1 and Polzeta repair structures that are recognized by the checkpoint despite their role in maintaining viability aft...

Def1 promotes the degradation of Pol3 for polymerase exchange to occur during D…

Daraba(A),Gali(VK),Halmai(M),Haracska(L),Unk… PLoS Biol 2014-01-00

...Rev1. Our results imply that TLS polymerases carry out DNA lesion bypass only after the Def1-assisted removal of Pol3 fr...

DNA polymerases and carcinogenesis.

Krutyakov(VM),Kravetskaya(TP) Biochemistry (Mosc) 2010-08-00

...Rev1, and terminal deoxynucleotidyl transferase, and only polymerases θ and σ manifest a slight 3'-exonuclease activity)...

Ribonucleotide incorporation by yeast DNA polymerase ζ.

Makarova(AV),Nick McElhinny(SA),Watts(BE),Ku… DNA Repair (Amst) 2014-06-00

...Rev1 gives comparable rNMP incorporation frequencies. These results suggest that ribonucleotide incorporation into DNA d...

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